Pfuetzer, Roland H. and Kruis, Wolfgang (2015). Management of diverticular disease. Nat. Rev. Gastroenterol. Hepatol., 12 (11). S. 629 - 639. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1759-5053

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Abstract

Diverticular disease is a common condition in Western countries and the incidence and prevalence of the disease is increasing. The pathogenetic factors involved include structural changes in the gut that increase with age, a diet low in fibre and rich in meat, changes in intestinal motility, the concept of enteric neuropathy and an underlying genetic background. Current treatment strategies are hampered by insufficient options to stratify patients according to individual risk. One of the main reasons is the lack of an all-encompassing classification system of diverticular disease. In response, the German Society for Gastroenterology and Digestive Diseases (DGVS) has proposed a classification system as part of its new guideline for the diagnosis and management of diverticular disease. The classification system includes five main types of disease: asymptomatic diverticulosis, acute uncomplicated and complicated diverticulitis, as well as chronic diverticular disease and diverticular bleeding. Here, we review prevention and treatment strategies stratified by these five main types of disease, from prevention of the first attack of diverticulitis to the management of chronic complications and diverticular bleeding.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Pfuetzer, Roland H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kruis, WolfgangUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-388156
DOI: 10.1038/nrgastro.2015.115
Journal or Publication Title: Nat. Rev. Gastroenterol. Hepatol.
Volume: 12
Number: 11
Page Range: S. 629 - 639
Date: 2015
Publisher: NATURE PUBLISHING GROUP
Place of Publication: NEW YORK
ISSN: 1759-5053
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
NONSTEROIDAL ANTIINFLAMMATORY DRUGS; ACUTE COLONIC DIVERTICULITIS; RANDOMIZED CLINICAL-TRIAL; LAPAROSCOPIC PERITONEAL-LAVAGE; LOWER GASTROINTESTINAL HEMORRHAGE; ELECTIVE SIGMOID RESECTION; IRRITABLE-BOWEL-SYNDROME; COMPLICATED DIVERTICULITIS; NATURAL-HISTORY; COMPUTED-TOMOGRAPHYMultiple languages
Gastroenterology & HepatologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/38815

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