Schroeder, Lars, Poetzsch, Bernd, Ruehl, Heiko, Gembruch, Ulrich ORCID: 0000-0001-8284-4669 and Merz, Waltraut M. (2015). Tranexamic Acid for Hyperfibrinolytic Hemorrhage During Conservative Management of Placenta Percreta. Obstet. Gynecol., 126 (5). S. 1012 - 1016. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 0029-7844

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Abstract

BACKGROUND:Complications of conservative management of abnormal placentation in which the placenta is left in situ for resorption include secondary hemorrhage, infection, and disseminated intravascular coagulation.CASE:A 41-year old woman received conservative treatment for placenta percreta. Nine weeks after delivery, she developed gingival bleeding, easy bruising, and moderate-to-severe vaginal bleeding. Hemostasis testing established the diagnosis of isolated hyperfibrinolysis; acute disseminated intravascular coagulation was excluded. Bleeding was successfully treated using the antifibrinolytic agent tranexamic acid. Eight weeks later uncomplicated curettage was performed.CONCLUSION:Isolated hyperfibrinolysis is a potential cause of bleeding during conservative management of placenta increta and percreta. Management of this treatment approach should include hemostasis monitoring, because hyperfibrinolysis can be successfully controlled using fibrinolysis inhibitors.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Schroeder, LarsUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Poetzsch, BerndUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ruehl, HeikoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gembruch, UlrichUNSPECIFIEDorcid.org/0000-0001-8284-4669UNSPECIFIED
Merz, Waltraut M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-388965
DOI: 10.1097/AOG.0000000000000915
Journal or Publication Title: Obstet. Gynecol.
Volume: 126
Number: 5
Page Range: S. 1012 - 1016
Date: 2015
Publisher: LIPPINCOTT WILLIAMS & WILKINS
Place of Publication: PHILADELPHIA
ISSN: 0029-7844
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
Obstetrics & GynecologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/38896

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