Universität zu Köln

Damasceno, Renato Wendell, Avgitidou, Georgia, Belfort, Rubens, Jr., Correa Dantas, Paulo Elias, Holbach, Leonard M. and Heindl, Ludwig M. (2015). Eyelid aging: pathophysiology and clinical management. Arq. Bras. Oftalmol., 78 (5). S. 328 - 332. SAO PAULO: CONSEL BRASIL OFTALMOLOGIA. ISSN 1678-2925

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Abstract

Life expectancy is increasing in most countries. With increasing age, many individuals may develop involutional ophthalmic diseases, such as eyelid aging. Dermatochalasis, ptosis, ectropion, and entropion are common disorders in middle-aged and older adults. This review outlines the pathophysiology and clinical management of these involutional eyelid disorders. Recently, a decrease in elastic fibers with ultrastructural abnormalities and an overexpression of elastin-degrading enzymes have been demonstrated in involutional ectropion and entropion. This may be the consequence of local ischemia, inflammation, and/or chronic mechanical stress. Eyelid aging with progressive loss of tone and laxity may affect the ocular surface and adnexal tissues, resulting in different clinical symptoms and signs. Surgical management depends on the appropriate correction of the underlying anatomical defect.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Damasceno, Renato Wendell UNSPECIFIED UNSPECIFIED UNSPECIFIED Avgitidou, Georgia UNSPECIFIED UNSPECIFIED UNSPECIFIED Belfort, Rubens, Jr. UNSPECIFIED UNSPECIFIED UNSPECIFIED Correa Dantas, Paulo Elias UNSPECIFIED UNSPECIFIED UNSPECIFIED Holbach, Leonard M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Heindl, Ludwig M. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-393748
DOI:	10.5935/0004-2749.20150087
Journal or Publication Title:	Arq. Bras. Oftalmol.
Volume:	78
Number:	5
Page Range:	S. 328 - 332
Date:	2015
Publisher:	CONSEL BRASIL OFTALMOLOGIA
Place of Publication:	SAO PAULO
ISSN:	1678-2925
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ISCHEMIA-REPERFUSION INJURY; INVOLUTIONAL ENTROPION; MATRIX METALLOPROTEINASES; ELASTIC FIBERS; RISK-FACTORS; ECTROPION; SKIN; AGE; HISTOPATHOLOGY; INVOLVEMENT Multiple languages Ophthalmology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/39374