Universität zu Köln

Tuchscherer, A. and Chemnitz, J. (2015). Hemolytic anemia. Internist, 56 (9). S. 1000 - 1006. NEW YORK: SPRINGER. ISSN 1432-1289

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Abstract

Hemolytic anemia can be caused by various hereditary or acquired diseases. Classification is usually based on corpuscular or extracorpuscular defects. Beside the anemia, laboratory testing indicates increased lactate dehydrogenase, unconjugated bilirubin and reticulocytes as well as reduced or absent plasma haptoglobin. Knowledge of further diagnostic procedures (e.g., Coombs test, schistocytes, hemoglobin electrophoresis or flow cytometric analysis) leads in many cases to an underlying disease with differentiated therapeutic options. Autoimmune hemolytic anemia (AIHA) is often associated with diseases as HIV, connective tissue disease, lymphomas or malignant tumors and the hemolytic process is preexisting in many cases. Thrombotic microvascular diseases (e.g., thrombotic thrombocytopenic purpura or hemolytic-uremic syndrome) are further important causes of hemolytic anemia which need immediate diagnosis and treatment.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Tuchscherer, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Chemnitz, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-394538
DOI:	10.1007/s00108-015-3661-8
Journal or Publication Title:	Internist
Volume:	56
Number:	9
Page Range:	S. 1000 - 1006
Date:	2015
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1432-1289
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language THROMBOTIC THROMBOCYTOPENIC PURPURA; PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA; COMPLEMENT INHIBITOR ECULIZUMAB; UREMIC SYNDROME; ADAMTS13; MICROANGIOPATHY; ASSOCIATION; ANTIBODIES; MODEL Multiple languages Medicine, General & Internal Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/39453