Universität zu Köln

Heilmann, K. E., Wagner, M., Riedel-Heller, S., Maier, W. and Jessen, F. (2015). Treating Late Life Depression with Antidepressants - A Summary of Recommendations in International Guidelines. Forschritte Neurol. Psychiatr., 83 (7). S. 381 - 391. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1439-3522

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Abstract

Late life depression is associated with severe health consequences, e.g. elevated risk of medical comorbidity and decreased quality of life. This paper summarizes the recommendations of the international guidelines on evidence-based pharmacological treatment of depression in late life in a systematic review. Pharmacological treatments for depression recommended by most of the guidelines, however, hardly address the issue of the possible side effects of antidepressants and other factors of multi-medication on the elderly. Different guidelines pay different degrees of attention to the specific group of geriatric patients. There is a lack of evidence-based treatment recommendation that takes into consideration the specific age-related issues of sensitivity to adverse effects or pharmacokinetic interaction. Further research is required to provide a database for more refined recommendations in guidelines.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Heilmann, K. E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wagner, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Riedel-Heller, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Maier, W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Jessen, F. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-399466
DOI:	10.1055/s-0035-1553315
Journal or Publication Title:	Forschritte Neurol. Psychiatr.
Volume:	83
Number:	7
Page Range:	S. 381 - 391
Date:	2015
Publisher:	GEORG THIEME VERLAG KG
Place of Publication:	STUTTGART
ISSN:	1439-3522
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language OLDER; METAANALYSIS; DULOXETINE; MANAGEMENT; EFFICACY; PEOPLE Multiple languages Clinical Neurology; Psychiatry Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/39946