Wieland, U. and Kreuter, A. (2015). HPV-induced anal lesions. Hautarzt, 66 (6). S. 439 - 446. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-1173

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Abstract

Human papillomavirus (HPV) infections belong to the most common sexually transmitted infections. To date, more than 200 completely classified HPV-types have been reported, and those belonging to the genus alpha predominantly infect the anogenital region. Condylomata acuminata are caused by the two low-risk types HPV6 and HPV11 in more than 90 % of cases. Treatment of genital warts might be either ablative (e.g. electrocautery, surgical excision, or laser therapy) or topical (e.g. podophyllotoxine, trichloroacetic acid, or imiquimod), and depends on the size, location, morphology and anatomical region. Recurrences after treatment are frequent. Therefore, combination therapies (e.g. topical and ablative) play an important role in daily routine. HIV-infected individuals, especially HIV-positive MSM, have a strongly increased risk for anal dysplasia and anal cancer. Condylomata acuminata and a large proportion of anal dysplasia and anal carcinoma are preventable by prophylactic HPV-vaccination.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Wieland, U.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kreuter, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-402673
DOI: 10.1007/s00105-015-3630-0
Journal or Publication Title: Hautarzt
Volume: 66
Number: 6
Page Range: S. 439 - 446
Date: 2015
Publisher: SPRINGER HEIDELBERG
Place of Publication: HEIDELBERG
ISSN: 1432-1173
Language: German
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
HUMAN-PAPILLOMAVIRUS INFECTION; HIV-POSITIVE MEN; ACTIVE ANTIRETROVIRAL THERAPY; RANDOMIZED CONTROLLED-TRIAL; SQUAMOUS-CELL CARCINOMA; INTRAEPITHELIAL NEOPLASIA; RISK-FACTORS; GENITAL WARTS; HOMOSEXUAL-MEN; FOLLOW-UPMultiple languages
DermatologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/40267

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