Universität zu Köln

Niemann, Catherin and Schneider, Marlon R. (2014). Hair type-specific function of canonical Wnt activity in adult mouse skin. Exp. Dermatol., 23 (12). S. 881 - 884. HOBOKEN: WILEY-BLACKWELL. ISSN 1600-0625

Full text not available from this repository.

Abstract

Wnt/-catenin signalling is a key regulator of hair follicle (HF) morphogenesis and life-long HF regeneration. In a recently published issue of Experimental Dermatology, Lei etal. report that sustained WNT10B supply and pathway activation in regenerating mouse HF increased the width of hair bulbs, hair shafts and the dermal papilla (DP), and enlarged the CD34(+) HF bulge cell compartment. Notably, WNT10B affected primarily zigzag HFs, while size and morphology of other HF types remained largely unaffected. Thus, these findings raise a number of questions regarding a HF type-specific function of Wnt/-catenin and on the role of the WNT-stimulated DP in this process.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Niemann, Catherin UNSPECIFIED UNSPECIFIED UNSPECIFIED Schneider, Marlon R. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-421767
DOI:	10.1111/exd.12509
Journal or Publication Title:	Exp. Dermatol.
Volume:	23
Number:	12
Page Range:	S. 881 - 884
Date:	2014
Publisher:	WILEY-BLACKWELL
Place of Publication:	HOBOKEN
ISSN:	1600-0625
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language DERMAL PAPILLA CELLS; BETA-CATENIN; STEM-CELLS; WNT/BETA-CATENIN; FOLLICLE MORPHOGENESIS; TRANSIENT ACTIVATION; GROWTH; DIFFERENTIATION; REGENERATION; EXPRESSION Multiple languages Dermatology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/42176