Wisplinghoff, Hilmar and Seifert, Harald (2014). Epidemiology and clinical features of Acinetobacter baumannii infections in humans. Berliner Munchener Tierarztl. Wochenschr., 127 (11-12). S. 447 - 458. HANNOVER: SCHLUETERSCHE VERLAGSGESELLSCHAFT MBH & CO KG. ISSN 1439-0299

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Abstract

Over the past 30 years, Acinetobacter (A.) baumannii has been increasingly recognized as an important human pathogen. In contrast to the non-baumannii Acinetobacter spp. which rarely cause diseases in humans, the members of the A. baumannii-group (A. baumannii, A. pittii and A. nosocomialis) are important nosocomial pathogens. A. baumannii itself has been implicated as a causative agent in various severe infections such as bloodstream infections, pneumonia, or meningitis, mainly in immunocompromised patients in the intensive care unit setting. The combination of intrinsic and increasing acquired resistance to various antimicrobial agents often limits the therapeutic options. Currently, none of the available antimicrobial agents with potential activity against Acinetobacter spp. such as, carbapenems, tigecycline, and colistin can be considered uniformly active against all A. baumannii strains. In addition, the incidence of multi- or pan-resistant A. baumannii-strains is increasing worldwide. Due to the unique combination of high resistance to adverse environmental conditions, the propensity for clonal spread and the extensive resistance to antimicrobial agents, A. baumannii is one of the most important bacterial pathogens of our time.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Wisplinghoff, HilmarUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Seifert, HaraldUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-425411
DOI: 10.2376/0005-9366-127-447
Journal or Publication Title: Berliner Munchener Tierarztl. Wochenschr.
Volume: 127
Number: 11-12
Page Range: S. 447 - 458
Date: 2014
Publisher: SCHLUETERSCHE VERLAGSGESELLSCHAFT MBH & CO KG
Place of Publication: HANNOVER
ISSN: 1439-0299
Language: German
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
BLOOD-STREAM INFECTIONS; MOLECULAR EPIDEMIOLOGY; RISK-FACTORS; HOSPITALS; STRAINS; RESISTANCE; MENINGITIS; CLONEMultiple languages
Veterinary SciencesMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/42541

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