Mohite, Prashant N., Sabashnikov, Anton ORCID: 0000-0002-6289-1035, Patil, Nikhil P., Saez, Diana Garcia, Zych, Bartlomiej, Popov, Aron F., Weymann, Alexander, Wahlers, Thorsten, Marczin, Nandor, DeRobertis, Fabio, Bahrami, Toufan, Amrani, Mohamed and Simon, Andre R. (2014). Short-term ventricular assist device in post-cardiotomy cardiogenic shock: factors influencing survival. J. Artif. Organs, 17 (3). S. 228 - 236. TOKYO: SPRINGER JAPAN KK. ISSN 1619-0904

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Abstract

Post-cardiotomy cardiogenic shock (PCCS) results in substantial morbidity and mortality, whereas refractory cases require mechanical circulatory support. The aim of this study was to evaluate factors influencing survival during short-term ventricular assist support in PCCS. In total, 154 CentriMag(A (R)) (Thoratec; CA, USA) devices were implanted for cardiogenic shock between 2004 and 2011 out of which 31 were for PCCS. A retrospective review was performed in 31 PCCS patients who required the CentriMag short-term VAD as a bridge to decision. Survivors and non-survivors were compared with respect to pre- and intra-operative characteristics as well as duration of short-term VAD support. Mean duration of support was 11.7 +/- A 15.4 days (range 1-65 days). Seventeen (54.83 %) patients died on support, 14 (45.16 %) were weaned off or upgraded to long-term device, while 11 (35.5 %) were discharged home. The overall survival to myocardial recovery and device explantation, or upgrade to a long-term VAD, was 41.9 % (n = 13) at the study cutoff. EuroSCORE II was significantly higher in non-survivors as compared to survivors (p = 0.047). The duration of short-term VAD support was significantly longer in survivors (p < 0.001). The CentriMag is a versatile, safe and effective short-term circulatory support for patients with PCCS as a bridge to decision which enables longer support and better recovery of both heart and end-organ function and thus may improve the survival of PCCS patients. Lower EuroSCORE may be essential for myocardial recovery in PCCS.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Mohite, Prashant N.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sabashnikov, AntonUNSPECIFIEDorcid.org/0000-0002-6289-1035UNSPECIFIED
Patil, Nikhil P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Saez, Diana GarciaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Zych, BartlomiejUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Popov, Aron F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Weymann, AlexanderUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wahlers, ThorstenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Marczin, NandorUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
DeRobertis, FabioUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bahrami, ToufanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Amrani, MohamedUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Simon, Andre R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-430152
DOI: 10.1007/s10047-014-0773-1
Journal or Publication Title: J. Artif. Organs
Volume: 17
Number: 3
Page Range: S. 228 - 236
Date: 2014
Publisher: SPRINGER JAPAN KK
Place of Publication: TOKYO
ISSN: 1619-0904
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
INTRAAORTIC BALLOON PUMP; EXPERIENCE; OUTCOMES; SUPPORT; SYSTEM; BRIDGEMultiple languages
Engineering, Biomedical; TransplantationMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/43015

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