Helmstaedter, Martin, Hoehne, Martin and Huber, Tobias B. ORCID: 0000-0001-7175-5062 (2014). A Brief Overview on IRM Function Across Evolution. J. Neurogenet., 28 (3-4). S. 264 - 270. ABINGDON: TAYLOR & FRANCIS LTD. ISSN 1563-5260

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Abstract

The description of the Rst protein by Karl-Friedrich Fischbach and colleagues was a milestone in the discovery of the irre cell recognition module (IRM). IRM proteins represent a family of immunoglobulin superfamily cell adhesion proteins that orchestrate intercellular adhesion and signaling events necessary for the development of various tissues. This review briefly summarizes the fundamental role of IRM proteins for neuronal wiring and filtration in organisms spanning the evolutionary distance from Drosophila (nephrocyte diaphragm) to humans (slit diaphragm).

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Helmstaedter, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hoehne, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Huber, Tobias B.UNSPECIFIEDorcid.org/0000-0001-7175-5062UNSPECIFIED
URN: urn:nbn:de:hbz:38-431221
DOI: 10.3109/01677063.2014.918976
Journal or Publication Title: J. Neurogenet.
Volume: 28
Number: 3-4
Page Range: S. 264 - 270
Date: 2014
Publisher: TAYLOR & FRANCIS LTD
Place of Publication: ABINGDON
ISSN: 1563-5260
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
IMMUNOGLOBULIN-LIKE PROTEIN; IRREC-RST PROTEIN; CHIASM-C-ROUGHEST; SLIT DIAPHRAGM; DROSOPHILA-MELANOGASTER; MYOBLAST FUSION; AXONAL PROJECTIONS; CELL-DEATH; NEPHRIN; GENEMultiple languages
Genetics & Heredity; NeurosciencesMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/43122

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