Heinzel, Alexander ORCID: 0000-0002-2430-4557, Mueller, Dirk, Behrendt, Florian F., Giovanella, Luca, Mottaghy, Felix M. and Verburg, Frederik A. (2014). Thyroid nodules with indeterminate cytology: molecular imaging with Tc-99m-methoxyisobutylisonitrile (MIBI) is more cost-effective than the AfirmaA (R) gene expression classifier. Eur. J. Nucl. Med. Mol. Imaging, 41 (8). S. 1497 - 1501. NEW YORK: SPRINGER. ISSN 1619-7089

Full text not available from this repository.

Abstract

Purpose To compare the cost-effectiveness of Tc-99m-methoxyisobutylisonitrile (MIBI) thyroid scintigraphy and the AfirmaA (R) gene expression classifier for the assessment of cytologically indeterminate thyroid nodules. Methods A decision tree model was used. Costs were calculated from the perspective of the German health insurance system. The robustness of the results was assessed with probabilistic sensitivity analyses using a Monte Carlo simulation. Results Life expectancy was 34.3 years (estimated costs per patient a,not sign1,459 - a,not sign2,224) for the MIBI scan and 34.1 years (estimated costs a,not sign3,560 - a,not sign4,071) for the molecular test. These results were confirmed by the Monte Carlo simulation. Conclusion MIBI thyroid scintigraphy is more cost-effective than the gene expression classifier.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Heinzel, AlexanderUNSPECIFIEDorcid.org/0000-0002-2430-4557UNSPECIFIED
Mueller, DirkUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Behrendt, Florian F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Giovanella, LucaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mottaghy, Felix M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Verburg, Frederik A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-433266
DOI: 10.1007/s00259-014-2760-4
Journal or Publication Title: Eur. J. Nucl. Med. Mol. Imaging
Volume: 41
Number: 8
Page Range: S. 1497 - 1501
Date: 2014
Publisher: SPRINGER
Place of Publication: NEW YORK
ISSN: 1619-7089
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
ASPIRATION-CYTOLOGY; MALIGNANCY; SCINTIGRAPHY; TC-99M-MIBIMultiple languages
Radiology, Nuclear Medicine & Medical ImagingMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/43326

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item