Universität zu Köln

Rhiem, K. and Schmutzler, R. K. (2014). Risk-adapted surveillance. Focus on familial breast and ovarian cancer. Bundesgesundheitsblatt-Gesund., 57 (3). S. 307 - 312. NEW YORK: SPRINGER. ISSN 1437-1588

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Abstract

Breast cancer surveillance programs for the general population are not adequate for the small number of women with hereditary breast and ovarian cancer syndrome. Breast cancer screening for women in Germany starts at the age of 50 years, but nearly half of all women with familial risk are already diagnosed with breast cancer at that time. Moreover, mammography alone is not suitable for an early diagnosis of breast cancer in young women from high-risk families. Their typical dense breast tissue causes a high rate of false-negative cases. Therefore, national and international prospective clinical trials were initiated to offer a multimodal breast cancer surveillance program including magnetic resonance tomography for the breast and semiannual screening intervals to women with BRCA1/2 mutations and those from high-risk families who tested negative for BRCA1/2 mutations. This program will currently be evaluated by the 15 centers of the German Consortium for Hereditary Breast and Ovarian Cancer.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Rhiem, K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmutzler, R. K. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-444362
DOI:	10.1007/s00103-013-1910-3
Journal or Publication Title:	Bundesgesundheitsblatt-Gesund.
Volume:	57
Number:	3
Page Range:	S. 307 - 312
Date:	2014
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1437-1588
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language BRCA2 MUTATION CARRIERS; SUSCEPTIBILITY GENE; HEREDITARY BREAST; WOMEN; MAMMOGRAPHY; PREDISPOSITION; MASTECTOMY; ULTRASOUND; MODEL Multiple languages Public, Environmental & Occupational Health Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/44436