Universität zu Köln

Hero, Barbara and Schleiermacher, Gudrun ORCID: 0000-0002-0133-5879 (2013). Update on Pediatric Opsoclonus Myoclonus Syndrome. Neuropediatrics, 44 (6). S. 324 - 330. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1439-1899

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Abstract

Opsoclonus myoclonus syndrome (dancing eye syndrome) is a rare paraneoplastic syndrome characterized by opsoclonus, myoclonus, and ataxia, usually accompanied by behavioral abnormalities. In adults, opsoclonus myoclonus syndrome has been reported in association with different types of cancer; whereas in children, the syndrome may be associated with neuroblastic tumors. Although a direct proof is lacking, the syndrome is assumed to be of autoimmune origin. The treatment is corticosteroid based with the addition of other immunosuppressive or immunomodulating drugs if intensification seems necessary. Because of the rarity of the disease, international collaborations as well on research as on therapeutic strategies are urgently needed. A European consortium just started a trial for this rare condition.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Hero, Barbara UNSPECIFIED UNSPECIFIED UNSPECIFIED Schleiermacher, Gudrun UNSPECIFIED orcid.org/0000-0002-0133-5879 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-470448
DOI:	10.1055/s-0033-1358604
Journal or Publication Title:	Neuropediatrics
Volume:	44
Number:	6
Page Range:	S. 324 - 330
Date:	2013
Publisher:	GEORG THIEME VERLAG KG
Place of Publication:	STUTTGART
ISSN:	1439-1899
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ATAXIA SYNDROME; PARANEOPLASTIC OPSOCLONUS; CHILDRENS CANCER; ANTINEURONAL ANTIBODIES; CEREBELLAR-ATAXIA; NEUROBLASTOMA; RITUXIMAB; AUTOANTIBODIES; FEATURES; THERAPY Multiple languages Clinical Neurology; Pediatrics Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/47044