Universität zu Köln

Schneider, A., Reiner, M. and Kolibay, F. (2012). Severe hypernatremia. Case report, pathophysiology and therapy. Anaesthesist, 61 (12). S. 1054 - 1059. NEW YORK: SPRINGER. ISSN 0003-2417

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Abstract

The case of a female patient with a suprasellar optic glioma is reported, who was admitted to the intensive care unit due to decompensated diabetes insipidus with hypernatremia of 194 mmol/l. The sodium concentration was reduced slowly over 4 days and the patient recovered without sequelae. Based on this case the article deals with the pathophysiology and therapy of hypernatremia. An increase in extracellular osmolarity leads to augmented production of intracellular osmolytes in order to maintain the cell volume constant. Due to this counterregulation correction of the sodium concentration must be done with caution.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schneider, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Reiner, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kolibay, F. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-477159
DOI:	10.1007/s00101-012-2108-z
Journal or Publication Title:	Anaesthesist
Volume:	61
Number:	12
Page Range:	S. 1054 - 1059
Date:	2012
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	0003-2417
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CELL-VOLUME; MORTALITY; MMOL/L; CARE; RISK Multiple languages Anesthesiology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/47715