Lutz, Manfred P., Zalcberg, John R., Ducreux, Michel ORCID: 0000-0001-8649-7449, Ajani, Jaffer A., Allum, William, Aust, Daniela, Bang, Yung-Jue, Cascinu, Stefano ORCID: 0000-0003-2215-0731, Hoelscher, Arnulf, Jankowski, Janusz ORCID: 0000-0003-2130-9181, Jansen, Edwin P. M., Kisslich, Ralf, Lordick, Florian, Mariette, Christophe, Moehler, Markus, Oyama, Tsuneo, Roth, Arnaud, Rueschoff, Josef, Ruhstaller, Thomas, Seruca, Raquel ORCID: 0000-0002-8851-4166, Stahl, Michael, Sterzing, Florian, van Cutsem, Eric, van der Gaast, Ate, van Lanschot, Jan, Ychou, Marc ORCID: 0000-0001-7378-9469 and Otto, Florian (2012). Highlights of the EORTC St. Gallen International Expert Consensus on the primary therapy of gastric, gastroesophageal and oesophageal cancer - Differential treatment strategies for subtypes of early gastroesophageal cancer. Eur. J. Cancer, 48 (16). S. 2941 - 2954. OXFORD: ELSEVIER SCI LTD. ISSN 1879-0852

Full text not available from this repository.

Abstract

The 1st St. Gallen EORTC Gastrointestinal Cancer Conference 2012 Expert Panel clearly differentiated treatment and staging recommendations for the various gastroesophageal cancers. For locally advanced gastric cancer (>= PT3N+), the preferred treatment modality was pre- and postoperative chemotherapy. The majority of panel members would also treat T2N+ or even T2N0 tumours with a similar approach mainly because pretherapeutic staging was considered highly unreliable. It was agreed that adenocarcinoma of the gastroesophageal junction (AEG) is classified best according to Siewert et al. Preoperative radiochemotherapy (RCT) is the preferred treatment for AEG type I and II tumours. For AEG type III, i.e. tumours which may be considered as gastric cancer, perioperative chemotherapy is the majority approach. For resectable squamous cell cancer of the oesophagus a clear majority recommended radiochemotherapy followed by surgery as optimal approach, irrespective of tumour size. In contrast, definitive RCT was judged appropriate for advanced tumours with extended lymph node involvement (N2) or for cancers of the upper oesophagus. Additional recommendations are presented on the use of endosonography, PET-CT scan and laparoscopy for staging and on the preferred approach to surgery. (c) 2012 Elsevier Ltd. All rights reserved.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Lutz, Manfred P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Zalcberg, John R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ducreux, MichelUNSPECIFIEDorcid.org/0000-0001-8649-7449UNSPECIFIED
Ajani, Jaffer A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Allum, WilliamUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Aust, DanielaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bang, Yung-JueUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cascinu, StefanoUNSPECIFIEDorcid.org/0000-0003-2215-0731UNSPECIFIED
Hoelscher, ArnulfUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jankowski, JanuszUNSPECIFIEDorcid.org/0000-0003-2130-9181UNSPECIFIED
Jansen, Edwin P. M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kisslich, RalfUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lordick, FlorianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mariette, ChristopheUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Moehler, MarkusUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Oyama, TsuneoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Roth, ArnaudUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rueschoff, JosefUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ruhstaller, ThomasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Seruca, RaquelUNSPECIFIEDorcid.org/0000-0002-8851-4166UNSPECIFIED
Stahl, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sterzing, FlorianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
van Cutsem, EricUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
van der Gaast, AteUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
van Lanschot, JanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ychou, MarcUNSPECIFIEDorcid.org/0000-0001-7378-9469UNSPECIFIED
Otto, FlorianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-479593
DOI: 10.1016/j.ejca.2012.07.029
Journal or Publication Title: Eur. J. Cancer
Volume: 48
Number: 16
Page Range: S. 2941 - 2954
Date: 2012
Publisher: ELSEVIER SCI LTD
Place of Publication: OXFORD
ISSN: 1879-0852
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
CLINICAL-PRACTICE GUIDELINES; DIAGNOSIS; MANAGEMENT; ADENOCARCINOMAMultiple languages
OncologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/47959

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item