Universität zu Köln

Fuks, Kateryna, Moebus, Susanne, Hertel, Sabine, Viehmann, Anja, Nonnemacher, Michael, Dragano, Nico, Moehlenkamp, Stefan, Jakobs, Hermann, Kessler, Christoph, Erbel, Raimund and Hoffmann, Barbara (2011). Long-Term Urban Particulate Air Pollution, Traffic Noise, and Arterial Blood Pressure. Environ. Health Perspect., 119 (12). S. 1706 - 1712. RES TRIANGLE PK: US DEPT HEALTH HUMAN SCIENCES PUBLIC HEALTH SCIENCE. ISSN 1552-9924

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Abstract

BACKGROUND: Recent studies have shown an association of short-term exposure to fine particulate matter (PM) with transient increases in blood pressure (BP), but it is unclear whether long-term exposure has an effect on arterial BP and hypertension. OBJECTIVES: We investigated the cross-sectional association of residential long-term PM exposure with arterial BP and hypertension, taking short-term variations of PM and long-term road traffic noise exposure into account. METHODS: We used baseline data (2000-2003) on 4,291 participants, 45-75 years of age, from the Heinz Nixdorf Recall Study, a population-based prospective cohort in Germany. Urban background exposure to PM with aerodynamic diameter <= 2.5 mu m (PM2.5) and <= 10 mu m (PM10) was assessed with a dispersion and chemistry transport model. We used generalized additive models, adjusting for short-term PM, meteorology, traffic proximity, and individual risk factors. RESULTS: An interquartile increase in PM2.5 (2.4 mu g/m(3)) was associated with estimated increases in mean systolic and diastolic BP of 1.4 mmHg [95% confidence interval (CI): 0.5, 2.3] and 0.9 mmHg (95% CI: 0.4, 1.4), respectively. The observed relationship was independent of long-term exposure to road traffic noise and robust to the inclusion of many potential confounders. Residential proximity to high traffic and traffic noise exposure showed a tendency toward higher BP and an elevated prevalence of hypertension. CONCLUSIONS: We found an association of long-term exposure to PM with increased arterial BP in a population-based sample. This finding supports our hypothesis that long-term PM exposure may promote atherosclerosis, with air-pollution induced increases in BP being one possible biological pathway.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Fuks, Kateryna UNSPECIFIED UNSPECIFIED UNSPECIFIED Moebus, Susanne UNSPECIFIED UNSPECIFIED UNSPECIFIED Hertel, Sabine UNSPECIFIED UNSPECIFIED UNSPECIFIED Viehmann, Anja UNSPECIFIED UNSPECIFIED UNSPECIFIED Nonnemacher, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Dragano, Nico UNSPECIFIED UNSPECIFIED UNSPECIFIED Moehlenkamp, Stefan UNSPECIFIED UNSPECIFIED UNSPECIFIED Jakobs, Hermann UNSPECIFIED UNSPECIFIED UNSPECIFIED Kessler, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED Erbel, Raimund UNSPECIFIED UNSPECIFIED UNSPECIFIED Hoffmann, Barbara UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-484359
DOI:	10.1289/ehp.1103564
Journal or Publication Title:	Environ. Health Perspect.
Volume:	119
Number:	12
Page Range:	S. 1706 - 1712
Date:	2011
Publisher:	US DEPT HEALTH HUMAN SCIENCES PUBLIC HEALTH SCIENCE
Place of Publication:	RES TRIANGLE PK
ISSN:	1552-9924
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language RISK-FACTORS; SUBCLINICAL ATHEROSCLEROSIS; EXPOSURE; MATTER Multiple languages Environmental Sciences; Public, Environmental & Occupational Health; Toxicology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/48435