Prenzel, Klaus L., Hoelscher, Arnulf H., Grabolle, Inga, Fetzner, Ulrich, Kleinert, Robert, Gutschow, Christian A. and Stippel, Dirk L. (2011). Impact of Duct-to-Mucosa Pancreaticojejunostomy with External Drainage of the Pancreatic Duct After Pancreaticoduodenectomy. J. Surg. Res., 171 (2). S. 558 - 563. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE. ISSN 1095-8673

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Abstract

Background. A variety of different techniques are established for the management of the pancreatic remnant after partial pancreaticoduodenectomy. Although pancreaticojejunostomy is one of the most favored methods, technical details are still under discussion. We report about a series of duct-to-mucosa pancreaticojejunostomies with total external drainage of the pancreaticduct. Patients and Methods. Between 1998 and 2007 257 patients underwent surgical therapy for malignant disease of the pancreas and the periampullary region and for chronic pancreatitis. Of these, 153 partial pancreaticoduodenectomies (85 pylorus preserving resections and 68 Whipple's procedures) were performed. In all of these cases, the pancreatic remnant was drained by a duct-to-mucosa pancreaticojejunostomy with external drainage of the pancreatic duct. Presence of postoperative pancreatic fistula (PPF) was defined according to the International Study Group on Pancreatic Fistula (ISGPF). Results. Postoperative mortality was 1.9%. The incidence of postoperative pancreatic fistula (PPF) was 19.6% according to the ISGPF criteria. Only one patient required re-laparotomy for complications caused by PPF. Patients with PPF had a significantly longer operation time (7.3 h versus 6.6 h; P = 0.041). Incidence of PPF was not influenced by histology. In all cases the fistulas resolved under conservative treatment. Conclusion. Duct-to-mucosa PJ with external drainage is a safe procedure to enteralize the pancreatic stump after partial pancreaticoduodenectomy. (C) 2011 Elsevier Inc. All rights reserved.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Prenzel, Klaus L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hoelscher, Arnulf H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Grabolle, IngaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fetzner, UlrichUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kleinert, RobertUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gutschow, Christian A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stippel, Dirk L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-484618
DOI: 10.1016/j.jss.2010.06.046
Journal or Publication Title: J. Surg. Res.
Volume: 171
Number: 2
Page Range: S. 558 - 563
Date: 2011
Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE
Place of Publication: SAN DIEGO
ISSN: 1095-8673
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
FISTULA; PANCREATICOGASTROSTOMY; RISK; PANCREATOJEJUNOSTOMY; RECONSTRUCTION; LEAKAGE; PANCREATOGASTROSTOMY; COMPLICATIONS; METAANALYSIS; ANASTOMOSISMultiple languages
SurgeryMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/48461

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