Guddat, S., Solymos, E., Orlovius, A., Thomas, A., Sigmund, G., Geyer, H., Thevis, M. and Schaenzer, W. (2011). High-throughput screening for various classes of doping agents using a new dilute-and-shoot' liquid chromatography-tandem mass spectrometry multi-target approach. Drug Test. Anal., 3 (11-12). S. 836 - 851. HOBOKEN: WILEY. ISSN 1942-7611

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Abstract

A new multi-target approach based on liquid chromatography electrospray ionization tandem mass spectrometry (LC-(ESI)-MS/MS) is presented to screen for various classes of prohibited substances using direct injection of urine specimens. With a highly sensitive new generation hybrid mass spectrometer classic groups of drugs for example, diuretics, beta2-agonists stimulants and narcotics are detectable at concentration levels far below the required limits.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Guddat, S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Solymos, E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Orlovius, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Thomas, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sigmund, G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Geyer, H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Thevis, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schaenzer, W.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-485737
DOI: 10.1002/dta.372
Journal or Publication Title: Drug Test. Anal.
Volume: 3
Number: 11-12
Page Range: S. 836 - 851
Date: 2011
Publisher: WILEY
Place of Publication: HOBOKEN
ISSN: 1942-7611
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
ANDROGEN RECEPTOR MODULATORS; HUMAN URINE; CONTROL PURPOSES; LC-MS/MS; DIURETICS; CONFIRMATION; METABOLITES; AGONISTS; OPIATES; STIMULANTSMultiple languages
Biochemical Research Methods; Chemistry, Analytical; Pharmacology & PharmacyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/48573

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