Gaisendrees, Christopher ORCID: 0000-0002-7232-3330, Walter, Sebastian G., Elderia, Ahmed ORCID: 0000-0002-6859-5384, Vollmer, Mattias, Kaya, Suereyya, Djordjevic, Ilija ORCID: 0000-0002-5810-8626, Eghbalzadeh, Kaveh, Sabashnikov, Anton, Kahlert, Heike Anelie, Deppe, Antje-Christin, Boll, Boris, Madershahian, Navid and Wahlers, Thorsten (2021). Adequate anticoagulation and ECMO therapy in COVID-19 patients with severe pulmonary embolism. Perfusion-UK, 36 (6). S. 575 - 582. LONDON: SAGE PUBLICATIONS LTD. ISSN 1477-111X

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Abstract

SARS-CoV-2 (COVID-19) infections have been recently shown to be associated with a high rate of thromboembolic events due to pro-coagulative mechanisms that have not yet been fully understood. This paper reports on a 55-year-old female COVID-19 patient with severe ARDS and pulmonary embolism (PE) complicated by cardiogenic shock after 12 days of hospitalization under initial prophylactic anticoagulation with low molecular weight heparin (LMWH). An ultima-ratio va (veno-arterial) ECMO implantation and subsequent rapid upgrade to vvaECMO due to insufficient oxygenation was performed. The patient developed severe coagulopathy with intrapulmonary bleeding. The present report aims to highlight and discuss the pros and cons of various anticoagulation strategies in COVID-19 patients focusing on current scientific debates to address this frequently observed complication in the current situation worldwide.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Gaisendrees, ChristopherUNSPECIFIEDorcid.org/0000-0002-7232-3330UNSPECIFIED
Walter, Sebastian G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Elderia, AhmedUNSPECIFIEDorcid.org/0000-0002-6859-5384UNSPECIFIED
Vollmer, MattiasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kaya, SuereyyaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Djordjevic, IlijaUNSPECIFIEDorcid.org/0000-0002-5810-8626UNSPECIFIED
Eghbalzadeh, KavehUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sabashnikov, AntonUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kahlert, Heike AnelieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Deppe, Antje-ChristinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Boll, BorisUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Madershahian, NavidUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wahlers, ThorstenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-564082
DOI: 10.1177/0267659120979887
Journal or Publication Title: Perfusion-UK
Volume: 36
Number: 6
Page Range: S. 575 - 582
Date: 2021
Publisher: SAGE PUBLICATIONS LTD
Place of Publication: LONDON
ISSN: 1477-111X
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
MANAGEMENTMultiple languages
Cardiac & Cardiovascular Systems; Peripheral Vascular DiseaseMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/56408

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