Universität zu Köln

Djordjevic, Ilija ORCID: 0000-0002-5810-8626, Deppe, Antje-Christin, Sabashnikov, Anton, Kuhn, Elmar, Eghbalzadeh, Kaveh, Merkle, Julia, Gerfer, Stephen ORCID: 0000-0002-6568-6766, Gaisendrees, Christopher, Ivanov, Borko, Moellenbeck, Lukas, Adler, Christoph, Rustenbach, Christian, Rahmanian, Parwis, Mader, Navid, Kuhn-Regnier, Ferdinand and Wahlers, Thorsten (2021). Concomitant ECMO And IABP Support in Postcardiotomy Cardiogenic Shock Patients. Heart Lung Circ., 30 (10). S. 1533 - 1540. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1444-2892

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Abstract

Objectives Simultaneous mechanical circulatory support (MCS) with intra-aortic balloon pump (IABP) to extracorporeal membrane oxygenation (ECMO) is common in postcardiotomy cardiogenic shock (PCS). This study aimed to analyse the effect of concomitant ECMO and IABP therapy on the short-term outcomes of patients with PCS. Methods Between March 2006 and March 2017, 172 consecutive patients with central (c) or peripheral (p) venoarterial ECMO therapy due to PCS were identified at the current institution and included in this retrospective analysis. Patients were divided into ECMO+IABP and ECMO alone groups. Further, the impact of ECMO flow direction was analysed for the groups. Results A total of 129 patients received ECMO+IABP support and 43 patients were treated with ECMO alone. Median ECMO duration did not differ between the groups (68 [34; 95] hours ECMO+IABP vs 44 [20; 103] hours ECMO; p=0.151). However, a trend toward a higher weaning rate was evident in ECMO+IABP patients (75 [58%] ECMO+IABP vs 18 [42%] ECMO; p=0.078). Concomitant IABP support with either cECMO (73% [n=24] cECMO+IABP vs 50% [n=11] ECMO; p=0.098) or pECMO (57% [n=55] ECMO+IABP vs 33% [n=7] ECMO; p=0.056) was also associated with a trend toward a higher weaning rate off ECMO. In-hospital mortality did not differ between the groups. Conclusion This analysis found that, independent of ECMO type, additional IABP support might increase ECMO weaning; however, it did not influence survival in PCS patients. Larger studies are necessary to further analyse the impact of this concomitant MSC therapy on clinical outcomes.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Djordjevic, Ilija UNSPECIFIED orcid.org/0000-0002-5810-8626 UNSPECIFIED Deppe, Antje-Christin UNSPECIFIED UNSPECIFIED UNSPECIFIED Sabashnikov, Anton UNSPECIFIED UNSPECIFIED UNSPECIFIED Kuhn, Elmar UNSPECIFIED UNSPECIFIED UNSPECIFIED Eghbalzadeh, Kaveh UNSPECIFIED UNSPECIFIED UNSPECIFIED Merkle, Julia UNSPECIFIED UNSPECIFIED UNSPECIFIED Gerfer, Stephen UNSPECIFIED orcid.org/0000-0002-6568-6766 UNSPECIFIED Gaisendrees, Christopher UNSPECIFIED UNSPECIFIED UNSPECIFIED Ivanov, Borko UNSPECIFIED UNSPECIFIED UNSPECIFIED Moellenbeck, Lukas UNSPECIFIED UNSPECIFIED UNSPECIFIED Adler, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED Rustenbach, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Rahmanian, Parwis UNSPECIFIED UNSPECIFIED UNSPECIFIED Mader, Navid UNSPECIFIED UNSPECIFIED UNSPECIFIED Kuhn-Regnier, Ferdinand UNSPECIFIED UNSPECIFIED UNSPECIFIED Wahlers, Thorsten UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-567808
DOI:	10.1016/j.hlc.2021.03.276
Journal or Publication Title:	Heart Lung Circ.
Volume:	30
Number:	10
Page Range:	S. 1533 - 1540
Date:	2021
Publisher:	ELSEVIER SCIENCE INC
Place of Publication:	NEW YORK
ISSN:	1444-2892
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language EXTRACORPOREAL MEMBRANE-OXYGENATION; INTRAAORTIC BALLOON PUMP; MECHANICAL CIRCULATORY SUPPORT; LIFE-SUPPORT; GRAFT FLOW; COUNTERPULSATION Multiple languages Cardiac & Cardiovascular Systems Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/56780