Universität zu Köln

Vedder, Vanessa, Schildgen, Verena, Lusebrink, Jessica, Tillmann, Ramona Liza, Domscheit, Birgitta, Windisch, Wolfram, Karagiannidis, Christian, Brockmann, Michael and Schildgen, Oliver ORCID: 0000-0003-4297-9627 (2021). Differential cytology profiles in bronchoalveolar lavage (BAL) in COVID-19 patients A descriptive observation and comparison with other corona viruses, Influenza virus, Haemophilus influenzae, and Pneumocystis jirovecii. Medicine (Baltimore), 100 (1). PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1536-5964

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Abstract

Brochoalvelolar lavages (BALs) from patients suffering from hospitalized infections with SARS-CoV-2, other corona viruses (human coronavirus (HCoV)-229E, HCoV-OC43, HCoV-NL63, and HCoV-HKU1), Influenza virus type A and B, Haemophilus influenzae and Pneumocystis jirovecii were compared cytopathologically. The aim of the study was to evaluate if the cellular profile detectable in BAL may be specific for the respective pathogens and could lead to diagnosis of COVID-19 even in the absence of PCR results. Differential cytology and flow cytometry datasets of 62 patients were observed and compared. We observed a significant association between individual cell pattern changes and the causing pathogen, but no general cell distribution pattern. The cytology pattern of the BAL fluid in COVID-19 is not specific enough to use it as a sole diagnostic criterion, although it may support clinical decision making

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Vedder, Vanessa UNSPECIFIED UNSPECIFIED UNSPECIFIED Schildgen, Verena UNSPECIFIED UNSPECIFIED UNSPECIFIED Lusebrink, Jessica UNSPECIFIED UNSPECIFIED UNSPECIFIED Tillmann, Ramona Liza UNSPECIFIED UNSPECIFIED UNSPECIFIED Domscheit, Birgitta UNSPECIFIED UNSPECIFIED UNSPECIFIED Windisch, Wolfram UNSPECIFIED UNSPECIFIED UNSPECIFIED Karagiannidis, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Brockmann, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Schildgen, Oliver UNSPECIFIED orcid.org/0000-0003-4297-9627 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-567840
DOI:	10.1097/MD.0000000000024256
Journal or Publication Title:	Medicine (Baltimore)
Volume:	100
Number:	1
Date:	2021
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1536-5964
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language Medicine, General & Internal Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/56784