Universität zu Köln

Elezagic, Dzemal, Johannis, Wibke, Burst, Volker, Klein, Florian and Streichert, Thomas (2021). Venous blood gas analysis in patients with COVID-19 symptoms in the early assessment of virus positivity. J. Lab. Med., 45 (1). S. 27 - 31. BERLIN: WALTER DE GRUYTER GMBH. ISSN 2567-9449

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Abstract

Objectives: Coronavirus disease 2019 (COVID-19) is currently a worldwide major health threat. Recognizing hypoxia in patients early on can have a considerable effect on therapy success and survival rate. Methods: We collected data using a standard blood gas analyzer from 50 patients and analyzed measurements of partial pressure of carbon dioxide-pCO(2), partial pressure of oxygen-pO(2) and oxygen saturation-sO(2), bicarbonate concentrations-HCO3- as well as ionized calcium concentrations. We further examined PCR test results for SARS-CoV-2 of the patients and analyzed differences between patients tested positive and those tested negative for the virus. Results: Venous pCO(2) was significantly higher whereas pO(2) and sO(2) were significantly lower in patients who tested positive for SARS-CoV-2. The pH, and ionized calcium concentrations of patients tested positive for the virus were significantly lower than in those tested negative. Conclusions: Symptomatic SARS-CoV-2-positive patients upon admission to the emergency room exhibit lower venous blood levels of oxygen, pH, and calcium and higher levels of carbon dioxide compared to symptomatic SARS-CoV2-negative patients. This blood gas analysis constellation could help in identifying SARS-CoV-2-positive patients more rapidly and identifying early signs of hypoxia.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Elezagic, Dzemal UNSPECIFIED UNSPECIFIED UNSPECIFIED Johannis, Wibke UNSPECIFIED UNSPECIFIED UNSPECIFIED Burst, Volker UNSPECIFIED UNSPECIFIED UNSPECIFIED Klein, Florian UNSPECIFIED UNSPECIFIED UNSPECIFIED Streichert, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-570812
DOI:	10.1515/labmed-2020-0126
Journal or Publication Title:	J. Lab. Med.
Volume:	45
Number:	1
Page Range:	S. 27 - 31
Date:	2021
Publisher:	WALTER DE GRUYTER GMBH
Place of Publication:	BERLIN
ISSN:	2567-9449
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language Medical Laboratory Technology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/57081