Universität zu Köln

Uhlig, Christopher and Labus, Jakob ORCID: 0000-0003-4498-0584 (2021). Volatile Versus Intravenous Anesthetics in Cardiac Anesthesia: a Narrative Review. Curr. Anesthesiol. Rep., 11 (3). S. 275 - 284. LONDON: SPRINGERNATURE. ISSN 2167-6275

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Abstract

Purpose of the Review The present review addresses clinicians and gives an overview about the experimental rationale for pharmacological conditioning associated with volatile anesthetics, opioids, and propofol; the current clinical data; and the technical considerations regarding the clinical routine in cardiac anesthesia. Recent Findings Volatile anesthetics have been standard of care for general anesthesia for cardiac surgery, especially while using cardiopulmonary bypass. The 2019 published MYRIAD trial was not able to show a difference in mortality or cardiac biomarkers for volatile anesthetics compared to total intravenous anesthesia (TIVA), raising the question of equivalence with respect to patient outcome. Reviewing the literature, the scientific foundation for the belief of clinically relevant conditioning by uninterrupted administration of a volatile anesthetic is weak. TIVA can also be performed safely in patients undergoing cardiac surgery.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Uhlig, Christopher UNSPECIFIED UNSPECIFIED UNSPECIFIED Labus, Jakob UNSPECIFIED orcid.org/0000-0003-4498-0584 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-575778
DOI:	10.1007/s40140-021-00466-1
Journal or Publication Title:	Curr. Anesthesiol. Rep.
Volume:	11
Number:	3
Page Range:	S. 275 - 284
Date:	2021
Publisher:	SPRINGERNATURE
Place of Publication:	LONDON
ISSN:	2167-6275
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CARDIOPULMONARY BYPASS; OCCUPATIONAL-EXPOSURE; PROPOFOL PHARMACOKINETICS; INFLAMMATORY RESPONSE; BISPECTRAL INDEX; CORONARY SURGERY; INFARCT-SIZE; SEVOFLURANE; ISOFLURANE; DESFLURANE Multiple languages Anesthesiology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/57577