Transcatheter Aortic Valve Implantation in Patients Who Cannot Undergo Transfemoral Access

Useini, Dritan ORCID: 0000-0002-8312-330X, Beluli, Blerta ORCID: 0000-0003-2155-0354, Christ, Hildegard, Schlomicher, Markus, Patsalis, Polykarpos, Haldenwang, Peter and Strauch, Justus . Transcatheter Aortic Valve Implantation in Patients Who Cannot Undergo Transfemoral Access. Thorac. Cardiovasc. Surg.. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1439-1902

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DOI:10.1055/s-0041-1727131

Abstract

Introduction Though transfemoral (TF) access has emerged as a gold standard access for patients with aortic stenosis who undergo transcatheter aortic valve implantation (TAVI), there has been no study that has characterized patients who cannot undergo TF access in detail. We aim to evaluate the contraindications for TF access, their incidence, classify them, and provide the outcomes of patients who failed to be TF candidates. Methods From 925 patients who underwent TAVI between February 2014 and May 2020 at our heart center, 130 patients failed to be TF candidates and underwent transapical-transcatheter aortic valve implantation (TA-TAVI). In this study, we included all those patients who failed to be TF candidates and underwent TA-TAVI using the third-generation balloon expandable valve (Edwards SAPIEN 3 valve [S3]) (116 patients; STS score 6.074.4; age 79.47). Results The incidence of patients unsuitable for TF access at our heart center was 14%. We classified this TAVI population into absolute contraindication for TF access n =84 (72.5%) and increased interventional risk for TF access n =32 (27.5%). After TA-TAVI of this specific population using S3, the in-hospital mortality and stroke were 1.7 and 1.7%, respectively. The vascular injury rate was 1.7%. We registered no paravalvular leakage >= 2. The pacemaker rate was 7.4%. The mean transvalvular pressure gradient was 8.7 mm Hg. Conclusion The incidence of patients who cannot undergo TF access or who are at high interventional risk is considerably high. TA-TAVI, supported with sufficient interventional experience and appropriate valve system, represents an excellent alternative for patients with distinct vasculopathy.

Item Type:

Journal Article

Creators:

Creators	Email	ORCID	ORCID Put Code
Useini, Dritan	UNSPECIFIED	orcid.org/0000-0002-8312-330X	UNSPECIFIED
Beluli, Blerta	UNSPECIFIED	orcid.org/0000-0003-2155-0354	UNSPECIFIED
Christ, Hildegard	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Schlomicher, Markus	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Patsalis, Polykarpos	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Haldenwang, Peter	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Strauch, Justus	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED