Universität zu Köln

Hoefer, Karolin Charlotte, Graf, Isabelle, Adams, Anne ORCID: 0000-0003-3286-1131, Kuhr, Kathrin, Plum, Georg, Schwendicke, Falk, Brockmeier, Konrad and Noack, Michael Johannes . Bacteraemia of oral origin in children-A Systematic review and network meta-analysis. Oral Dis.. HOBOKEN: WILEY. ISSN 1601-0825

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Abstract

Objectives To systematically review the prevalence of bacteraemia, triggered by dental intervention and home oral hygiene practices, in children. The network meta-analysis (NMA) quantitatively compared the risk of bacteraemia triggered by dental extractions and home and professional cleaning procedures. Materials and Methods Clinical trials with the outcome bacteraemia in children were searched. The NMA was performed using the frequentist weighted least-squares approach comparing the odds ratios (OR) of different interventions. Results Among 11 of 13 studies, dental treatment was performed under general anaesthesia. In 2,381 patients, bacteraemia occurred in 38.7%-56% patients following single-tooth extractions, in 22%-46% after manual toothbrushing (MTB), and in 26%-78% after power toothbrushing (PTB). When MTB was set as the reference (OR 1), rubber cup polishing showed a slightly higher risk (OR 1.26) of bacteraemia. PTB presented a higher risk (OR 1.79-2.27) than with single-tooth extractions (OR 1.55) but lower than that with multiple extractions (OR 2.55). Conclusion Daily use of MTB and routine professional cleaning were associated with the lowest risk of developing bacteraemia in children with gingivitis, almost as much as with a single-tooth extractions. Improved plaque control with PTB increased the risk of bacteraemia. There is limited evidence on gingivitis-free and systemically-diseased children.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Hoefer, Karolin Charlotte UNSPECIFIED UNSPECIFIED UNSPECIFIED Graf, Isabelle UNSPECIFIED UNSPECIFIED UNSPECIFIED Adams, Anne UNSPECIFIED orcid.org/0000-0003-3286-1131 UNSPECIFIED Kuhr, Kathrin UNSPECIFIED UNSPECIFIED UNSPECIFIED Plum, Georg UNSPECIFIED UNSPECIFIED UNSPECIFIED Schwendicke, Falk UNSPECIFIED UNSPECIFIED UNSPECIFIED Brockmeier, Konrad UNSPECIFIED UNSPECIFIED UNSPECIFIED Noack, Michael Johannes UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-580898
DOI:	10.1111/odi.13957
Journal or Publication Title:	Oral Dis.
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1601-0825
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language INFECTIVE ENDOCARDITIS; DENTAL BACTEREMIA; PERIODONTITIS; EPIDEMIOLOGY; INDIVIDUALS; PREVALENCE; STATEMENT; INTENSITY; RISK Multiple languages Dentistry, Oral Surgery & Medicine Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/58089