Steinkamp, Simon R., Fink, Gereon R. ORCID: 0000-0002-8230-1856, Vossel, Simone ORCID: 0000-0002-6351-8849 and Weidner, Ralph ORCID: 0000-0002-4502-0166 (2022). Simultaneous modeling of reaction times and brain dynamics in a spatial cueing task. Hum. Brain Mapp., 43 (6). S. 1850 - 1868. HOBOKEN: WILEY. ISSN 1097-0193

Full text not available from this repository.

Abstract

Understanding how brain activity translates into behavior is a grand challenge in neuroscientific research. Simultaneous computational modeling of both measures offers to address this question. The extension of the dynamic causal modeling (DCM) framework for blood oxygenation level-dependent (BOLD) responses to behavior (bDCM) constitutes such a modeling approach. However, only very few studies have employed and evaluated bDCM, and its application has been restricted to binary behavioral responses, limiting more general statements about its validity. This study used bDCM to model reaction times in a spatial attention task, which involved two separate runs with either horizontal or vertical stimulus configurations. We recorded fMRI data and reaction times (n= 26) and compared bDCM with classical DCM and a behavioral Rescorla-Wagner model using Bayesian model selection and goodness of fit statistics. Results indicate that bDCM performed equally well as classical DCM when modeling BOLD responses and as good as the Rescorla-Wagner model when modeling reaction times. Although our data revealed practical limitations of the current bDCM approach that warrant further investigation, we conclude that bDCM constitutes a promising method for investigating the link between brain activity and behavior.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Steinkamp, Simon R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fink, Gereon R.UNSPECIFIEDorcid.org/0000-0002-8230-1856UNSPECIFIED
Vossel, SimoneUNSPECIFIEDorcid.org/0000-0002-6351-8849UNSPECIFIED
Weidner, RalphUNSPECIFIEDorcid.org/0000-0002-4502-0166UNSPECIFIED
URN: urn:nbn:de:hbz:38-581175
DOI: 10.1002/hbm.25758
Journal or Publication Title: Hum. Brain Mapp.
Volume: 43
Number: 6
Page Range: S. 1850 - 1868
Date: 2022
Publisher: WILEY
Place of Publication: HOBOKEN
ISSN: 1097-0193
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
VENTRAL ATTENTION SYSTEMS; EFFECTIVE CONNECTIVITY; PERMUTATION TESTS; VISUAL-ATTENTION; DEPRESSION; WORKING; NEGLECT; STROKE; MEMORY; FMRIMultiple languages
Neurosciences; Neuroimaging; Radiology, Nuclear Medicine & Medical ImagingMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/58117

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item