Iannizzi, Claire ORCID: 0000-0002-6130-5997, Dorando, Elena, Burns, Jacob, Weibel, Stephanie, Dooley, Clare ORCID: 0000-0002-4112-3571, Wakeford, Helen, Estcourt, Lise J., Skoetz, Nicole ORCID: 0000-0003-4744-6192 and Piechotta, Vanessa (2022). Methodological challenges for living systematic reviews conducted during the COVID-19 pandemic: A concept paper. J. Clin. Epidemiol., 141. S. 82 - 90. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1878-5921

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Abstract

Background: A living systematic review (LSR) is an emerging review type that makes use of continual updating. In the COVID-19 pandemic, we were confronted with a shifting epidemiological landscape, clinical uncertainties and evolving evidence. These unexpected challenges compelled us to amend standard LSR methodology. Objective and outline: Our primary objective is to discuss some challenges faced when conducting LSRs in the context of the COVID-19 pandemic, and to provide methodological guidance for others doing similar work. Based on our experience and lessons learned from two Cochrane LSRs and challenges identified in several non-Cochrane LSRs, we highlight methodological considerations, particularly with regards to the study design, interventions and comparators, changes in outcome measure, and the search strategy. We discuss when to update, or rather when not to update the review, and the importance of transparency when reporting changes. Lessons learned and conclusion: We learned that a LSR is a very suitable review type for the pandemic context, even in the face of new methodological and clinical challenges. Our experience showed that the decision for updating a LSR depends not only on the evolving disease or emerging evidence, but also on the individual review question and the review teams' resources. (c) 2021 Elsevier Inc. All rights reserved.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Iannizzi, ClaireUNSPECIFIEDorcid.org/0000-0002-6130-5997UNSPECIFIED
Dorando, ElenaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Burns, JacobUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Weibel, StephanieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dooley, ClareUNSPECIFIEDorcid.org/0000-0002-4112-3571UNSPECIFIED
Wakeford, HelenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Estcourt, Lise J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Skoetz, NicoleUNSPECIFIEDorcid.org/0000-0003-4744-6192UNSPECIFIED
Piechotta, VanessaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-589385
DOI: 10.1016/j.jclinepi.2021.09.013
Journal or Publication Title: J. Clin. Epidemiol.
Volume: 141
Page Range: S. 82 - 90
Date: 2022
Publisher: ELSEVIER SCIENCE INC
Place of Publication: NEW YORK
ISSN: 1878-5921
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
Health Care Sciences & Services; Public, Environmental & Occupational HealthMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/58938

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