Universität zu Köln

Cruz-Aguilar, Rebeca, Carney, Jonathan, Mondaini, Vanessa, Vehreschild, Maria J. G. T., Griskaitis, Matas, Salmanton-Garcia, Jon, Boell, Boris, Kochanek, Matthias, Seifert, Harald, Biehl, Lena M. and Farowski, Fedja (2021). A quality improvement study on the reduction of central venous catheter-associated bloodstream infections by use of self-disinfecting venous access caps (STERILE). Am. J. Infect. Control, 49 (5). S. 586 - 593. NEW YORK: MOSBY-ELSEVIER. ISSN 1527-3296

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Abstract

Background: Contamination of the catheter hub is an important source of central line-associated bloodstream infections (CLABSI); catheter hub caps incorporating a 70% isopropyl alcohol aim are designed to reduce contamination and hence CLABSI rates. Supporting data in high-risk hematological and oncological patients on the clinical effectiveness of this approach are sparse. Methods: We conducted a before-after single center study accompanying the introduction of such caps at our department. Retrospective data from the year prior to the introduction were compared to 1 year of prospective data. Results: The control and antiseptic barrier cap (ABC) groups consisted of 309 and 289 patients presenting a CLABSI rate of 15.28 and 10.38 per 1,000 catheter days (P= .042), respectively. However, after multivariate analysis, ABCs were not identified as a statistically significant independent protective factor for the occurrence of CLABSI (hazard ratio 0.69, P= .120). There was no significant difference between the groups with respect to time to CLABSI (P= .681), nor the proportion of catheters removed due to suspicion of infection (P= .076). Conclusions: The introduction of ABCs in this high-risk population did not significantly alter CLABSI rates. (c) 2020 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Cruz-Aguilar, Rebeca UNSPECIFIED UNSPECIFIED UNSPECIFIED Carney, Jonathan UNSPECIFIED UNSPECIFIED UNSPECIFIED Mondaini, Vanessa UNSPECIFIED UNSPECIFIED UNSPECIFIED Vehreschild, Maria J. G. T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Griskaitis, Matas UNSPECIFIED UNSPECIFIED UNSPECIFIED Salmanton-Garcia, Jon UNSPECIFIED UNSPECIFIED UNSPECIFIED Boell, Boris UNSPECIFIED UNSPECIFIED UNSPECIFIED Kochanek, Matthias UNSPECIFIED UNSPECIFIED UNSPECIFIED Seifert, Harald UNSPECIFIED UNSPECIFIED UNSPECIFIED Biehl, Lena M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Farowski, Fedja UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-589521
DOI:	10.1016/j.ajic.2020.09.002
Journal or Publication Title:	Am. J. Infect. Control
Volume:	49
Number:	5
Page Range:	S. 586 - 593
Date:	2021
Publisher:	MOSBY-ELSEVIER
Place of Publication:	NEW YORK
ISSN:	1527-3296
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CONTAMINATION; ONCOLOGY; HEMATOLOGY; GUIDELINES; MANAGEMENT; DIAGNOSIS; CULTURES; SOCIETY; IMPACT Multiple languages Public, Environmental & Occupational Health; Infectious Diseases Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/58952