Zimmermann, Kristin, Mostafaei, Hadi ORCID: 0000-0001-5596-1771, Heidenreich, Axel, Schmelz, Hans U., Shariat, Shahrokh F. and Mori, Keiichiro (2021). Health-related quality of life in bladder cancer patients: bladder cancer-specific instruments and domains. Part 2. Curr. Opin. Urol., 31 (4). S. 304 - 315. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1473-6586

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Abstract

Purpose of review Several instruments have been designed to evaluate health-related quality of life (HRQoL) in patients with bladder cancer (BC). However, they vary in purpose, domains, and quality. To identify QoL instruments that have been validated for BC patients and to critically assess their domains and limitations. Recent findings Of the 11 instruments identified, seven have been externally validated. Of these, four can be used across all disease states; two are available for QoL assessment in patients with non-muscle invasive bladder cancer (NMIBC); and the European Organisation for Research and Treatment of Cancer (EORTC) module is intended for use together with a generic cancer-specific tool. Of the three instruments available to assess QoL in patients with muscle invasive bladder cancer (MIBC), EORTC Quality of Life Questionnaire-Bladder Cancer Muscle Invasive30 (QLQ-BLM30) and Functional Assessment of Cancer Therapy-Bladder-Cystectomy (FACT-Bl-Cys) need to be used each with their respective generic core questionnaire, whereas Ileal Orthotopic Neobladder-Pro Questionnaire is intended only to evaluate patients who have received an orthotopic neobladder. The core domains assessed by these instruments include social functioning, mental health, physical function, urinary function and sexual function. No optimal BC-specific QoL instruments exist. Multiple cancer- and BC-specific instruments are required to cover each of the relevant domains. Selected tools should be reviewed within the context of specific research objectives.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Zimmermann, KristinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mostafaei, HadiUNSPECIFIEDorcid.org/0000-0001-5596-1771UNSPECIFIED
Heidenreich, AxelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schmelz, Hans U.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Shariat, Shahrokh F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mori, KeiichiroUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-599679
DOI: 10.1097/MOU.0000000000000894
Journal or Publication Title: Curr. Opin. Urol.
Volume: 31
Number: 4
Page Range: S. 304 - 315
Date: 2021
Publisher: LIPPINCOTT WILLIAMS & WILKINS
Place of Publication: PHILADELPHIA
ISSN: 1473-6586
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
RADICAL CYSTECTOMY; URINARY-DIVERSION; OUTCOMES; QUESTIONNAIRE; METAANALYSIS; VALIDATION; CARCINOMA; IMPACTMultiple languages
Urology & NephrologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/59967

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