Bonadonna, Patrizia, Brockow, Knut, Niedoszytko, Marek, Elberink, Hanneke Oude, Akin, Cem, Nedoszytko, Boguslaw ORCID: 0000-0002-6286-0693, Butterfield, Joseph H., Alvarez-Twose, Ivan, Sotlar, Karl, Schwaab, Juliana, Jawhar, Mohamad, Castells, Mariana, Sperr, Wolfgang R., Hermine, Olivier, Gotlib, Jason, Zanotti, Roberta, Reiter, Andreas, Broesby-Olsen, Sigurd, Bindslev-Jensen, Carsten ORCID: 0000-0002-8940-038X, Schwartz, Lawrence B., Horny, Hans-Peter, Radia, Deepti, Triggiani, Massimo, Sabato, Vito, Carter, Melody C., Siebenhaar, Frank, Orfao, Alberto, Grattan, Clive, Metcalfe, Dean D., Arock, Michel, Gulen, Theo, Hartmann, Karin ORCID: 0000-0002-4595-8226 and Valent, Peter ORCID: 0000-0003-0456-5095 (2021). COVID-19 Vaccination in Mastocytosis: Recommendations of the European Competence Network on Mastocytosis (ECNM) and American Initiative in Mast Cell Diseases (AIM). J. Allergy Clin. Immunol.-Pract., 9 (6). S. 2139 - 2145. AMSTERDAM: ELSEVIER. ISSN 2213-2201

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Abstract

Mastocytosis is a neoplasm characterized by an accumulation of mast cells in various organs and increased risk for severe anaphylaxis in patients with concomitant allergies. Coronavirus disease 2019 (COVID-19) is a pandemic that is associated with a relatively high rate of severe lung disease and mortality. The mortality is particularly high in those with certain comorbidities and increases with age. Recently, several companies have developed an effective vaccination against COVID-19. Although the reported frequency of severe side effects is low, there is an emerging discussion about the safety of COVID-19 vaccination in patients with severe allergies and mastocytosis. However, even in these patients, severe adverse reactions are rare. We therefore recommend the broad use of COVID-19 vaccination in patients with mastocytosis on a global basis. The only well-established exception is a known or suspected allergy against a constituent of the vaccine. Safety measures, including premedication and postvaccination observation, should be considered in all patients with mastocytosis, depending on the individual personal risk and overall situation in each case. The current article provides a summary of published data, observations, and expert opinion that form the basis of these recommendations. (C) 2021 American Academy of Allergy, Asthma & Immunology

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Bonadonna, PatriziaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Brockow, KnutUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Niedoszytko, MarekUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Elberink, Hanneke OudeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Akin, CemUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nedoszytko, BoguslawUNSPECIFIEDorcid.org/0000-0002-6286-0693UNSPECIFIED
Butterfield, Joseph H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Alvarez-Twose, IvanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sotlar, KarlUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schwaab, JulianaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jawhar, MohamadUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Castells, MarianaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sperr, Wolfgang R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hermine, OlivierUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gotlib, JasonUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Zanotti, RobertaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Reiter, AndreasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Broesby-Olsen, SigurdUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bindslev-Jensen, CarstenUNSPECIFIEDorcid.org/0000-0002-8940-038XUNSPECIFIED
Schwartz, Lawrence B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Horny, Hans-PeterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Radia, DeeptiUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Triggiani, MassimoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sabato, VitoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Carter, Melody C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Siebenhaar, FrankUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Orfao, AlbertoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Grattan, CliveUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Metcalfe, Dean D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Arock, MichelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gulen, TheoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hartmann, KarinUNSPECIFIEDorcid.org/0000-0002-4595-8226UNSPECIFIED
Valent, PeterUNSPECIFIEDorcid.org/0000-0003-0456-5095UNSPECIFIED
URN: urn:nbn:de:hbz:38-607725
DOI: 10.1016/j.jaip.2021.03.041
Journal or Publication Title: J. Allergy Clin. Immunol.-Pract.
Volume: 9
Number: 6
Page Range: S. 2139 - 2145
Date: 2021
Publisher: ELSEVIER
Place of Publication: AMSTERDAM
ISSN: 2213-2201
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
HYMENOPTERA VENOM ALLERGY; SYSTEMIC MASTOCYTOSIS; FATAL ANAPHYLAXIS; RISK; CLASSIFICATION; DISORDERS; PREVENTION; MANAGEMENT; SYMPTOMS; HYPERSENSITIVITYMultiple languages
Allergy; ImmunologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/60772

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