Wienemann, Hendrik, Mauri, Victor, Ochs, Laurin, Koerber, Maria Isabel, Eghbalzadeh, Kaveh, Iliadis, Christos, Halbach, Marcel, Wahlers, Thorsten, Baldus, Stephan, Adam, Matti and Kuhn, Elmar . Contemporary treatment of mitral valve disease with transcatheter mitral valve implantation. Clin. Res. Cardiol.. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1861-0692

Full text not available from this repository.

Abstract

Background Transcatheter mitral valve implantation (TMVI) with self-expanding (SAV) or balloon-expandable (BAV) valves are rising as promising treatment options for high-risk patients with symptomatic mitral valve (MVD) disease unsuitable for alternative treatment options. Aims The aim of this study was to examine the clinical, procedural and outcome parameters of patients undergoing SAV or BAV for MVD. Methods In this observational and single-center case series, fifteen consecutive patients treated with the Tendyne Mitral Valve System (SAV) and thirty-one patients treated with SAPIEN prosthesis (BAV) were included. Results The patients (aged 78 years [interquartile range (IQR): 65.5 to 83.1 years], 41% women, EuroSCORE II 10.3% [IQR: 5.5 to 17.0%] were similar regarding baseline characteristics, despite a higher rate of prior heart valve surgery and prevalence of MV stenosis in the SAV-group. At discharge, the SAV-group had a mean transvalvular gradient of 4 2 mmHg, whereas the BAV-group had a mean transvalvular gradient of 6.2 mmHg None or trace paravalvular leakage (PVL) was assessed in 85% in SAV-group and 80% in the BAV-group. 320 day all-cause and cardiac mortality rates were comparable in both groups (SAV: 26.7% vs BAV: 20%, p = 0.60). Four deaths occurred early in the SAV-group until 32 days of follow-up. Conclusions In high-risk patients with MVD, TMVI presents a promising treatment option with encouraging mid-term outcomes and good valve durability. TMVI either with BAV or SAV may be developed to an established treatment option. [GRAPHICS] .

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Wienemann, HendrikUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mauri, VictorUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ochs, LaurinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Koerber, Maria IsabelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Eghbalzadeh, KavehUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Iliadis, ChristosUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Halbach, MarcelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wahlers, ThorstenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Baldus, StephanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Adam, MattiUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kuhn, ElmarUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-661192
DOI: 10.1007/s00392-022-02095-y
Journal or Publication Title: Clin. Res. Cardiol.
Publisher: SPRINGER HEIDELBERG
Place of Publication: HEIDELBERG
ISSN: 1861-0692
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
VALVULAR HEART-DISEASE; EUROPEAN ASSOCIATION; ANNULOPLASTY RINGS; AMERICAN-COLLEGE; TASK-FORCE; IN-VALVE; REPLACEMENT; REGURGITATION; GUIDELINES; OUTCOMESMultiple languages
Cardiac & Cardiovascular SystemsMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/66119

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item