Universität zu Köln

Gaisendrees, Christopher ORCID: 0000-0002-7232-3330, Gerfer, Stephen, Schroeder, Charlotte, Schlachtenberger, Georg, Walter, Sebastian, Ivanov, Borko, Eghbalzadeh, Kaveh, Luehr, Maximilian ORCID: 0000-0002-0645-1764, Djordjevic, Ilija ORCID: 0000-0002-5810-8626, Rahmanian, Parwis, Mader, Navid, Kuhn-Regnier, Ferdinand and Wahlers, Thorsten (2022). Benign and malignant cardiac masses: long-term outcomes after surgical resection. Expert Rev. Anticancer Ther, 22 (10). S. 1153 - 1159. ABINGDON: TAYLOR & FRANCIS LTD. ISSN 1744-8328

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Abstract

Introduction Cardiac tumors represent a rare and heterogenous pathologic entity, with a cumulative incidence of up to 0.02%. This study aimed to investigate one of the largest patient cohorts published for clinical presentation and long-term outcomes after surgical resection. Areas covered Between 2009 and 2021, 183 consecutive patients underwent surgery for tumor excision in our center. Preoperative baseline characteristics, intraoperative data, and long-term survival were analyzed. The diagnosis was confirmed postoperatively by histology and Immunohistochemical investigations. Kaplan-Meier curves assessed survival, and the Cox proportional hazards model, was used to identify prognostic factors for overall survival. Results This series included 183 consecutive patients; most (n = 169, 92.3%) were diagnosed with benign cardiac masses. The mean age of patients was 60 +/- 16 years, and 48% (n = 88) were females. The largest group of tumors was myxoma (n = 98; 54%). The most common malignant tumor type was sarcoma (n = 5; 2.7%). The mean hospital stay was 11 +/- 6.5 days, and all-cause mortality after ten years was 14%. Expert Opinion Surgery represents the gold standard in treating primary cardiac tumors; in benign tumors, it is highly effective and curative, whereas, in malignant tumors, it remains associated with more prolonged survival.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Gaisendrees, Christopher UNSPECIFIED orcid.org/0000-0002-7232-3330 UNSPECIFIED Gerfer, Stephen UNSPECIFIED UNSPECIFIED UNSPECIFIED Schroeder, Charlotte UNSPECIFIED UNSPECIFIED UNSPECIFIED Schlachtenberger, Georg UNSPECIFIED UNSPECIFIED UNSPECIFIED Walter, Sebastian UNSPECIFIED UNSPECIFIED UNSPECIFIED Ivanov, Borko UNSPECIFIED UNSPECIFIED UNSPECIFIED Eghbalzadeh, Kaveh UNSPECIFIED UNSPECIFIED UNSPECIFIED Luehr, Maximilian UNSPECIFIED orcid.org/0000-0002-0645-1764 UNSPECIFIED Djordjevic, Ilija UNSPECIFIED orcid.org/0000-0002-5810-8626 UNSPECIFIED Rahmanian, Parwis UNSPECIFIED UNSPECIFIED UNSPECIFIED Mader, Navid UNSPECIFIED UNSPECIFIED UNSPECIFIED Kuhn-Regnier, Ferdinand UNSPECIFIED UNSPECIFIED UNSPECIFIED Wahlers, Thorsten UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-664497
DOI:	10.1080/14737140.2022.2116006
Journal or Publication Title:	Expert Rev. Anticancer Ther
Volume:	22
Number:	10
Page Range:	S. 1153 - 1159
Date:	2022
Publisher:	TAYLOR & FRANCIS LTD
Place of Publication:	ABINGDON
ISSN:	1744-8328
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language TUMORS Multiple languages Oncology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/66449