Universität zu Köln

Ivanov, Borko, Djordjevic, Ilija ORCID: 0000-0002-5810-8626, Sabashnikov, Anton, Sindhu, Dirk, Hink, Stephan, Eghbalzadeh, Kaveh, Gerfer, Stephen ORCID: 0000-0002-6568-6766, Gaisendrees, Christopher, Schlachtenberger, Georg ORCID: 0000-0001-7118-8432, Rustenbach, Christian ORCID: 0000-0003-2178-8397, Seuthe, Katharina, Regnier, Kuhn, Mader, Navid, Pfister, Roman, Zeriouh, Mohamed, Rahmanian, Parwis and Wahlers, Thorsten (2022). Impact of Ischaemic and Dilated Cardiomyopathy on Short-Term and Long-Term Survival After Ventricular Assist Device Implantation: A Single-Centre Experience. Heart Lung Circ., 31 (3). S. 383 - 390. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1444-2892

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Abstract

Background Prognosis of patients with end-stage heart failure is known to be impacted by the aetiology of heart failure (HF). Ischaemic cardiomyopathy (ICM) and dilated cardiomyopathy (DCM) are the most frequent pa-thologies necessitating ventricular assist device (VAD) support in these patients. However, the specific impact of ICM and DCM in clinical outcomes after VAD implantation remains unclear. Therefore, this study aimed to analyse clinical differences in ICM and DCM patients after LVAD surgery from the current institution. Methods All consecutive patients from the LVAD centre were included in this retrospective study. To analyse specific differences in in-hospital outcomes, patients were divided into two groups: ICM and DCM. Long -term follow-up was calculated by Kaplan-Meier estimation of survival. Results Between January 2010 and July 2020, 60 consecutive patients underwent LVAD implantation at the insti-tution: 36 patients (60%) were supported due to end-stage ICM and 24 patients (40%) in regard of therapy-refractory DCM. Baseline characteristics showed no between-group differences. The ICM patients showed a clear trend to higher amount of additional cardiac procedures during VAD surgery (36% ICM vs 12% DCM; p=0.052). In-hospital mortality was comparable between ICM and DCM patients (36% ICM vs 21% DCM; p=0.206). A trend towards higher frequency of pump thrombosis was seen in DCM patients (p=0.080). Long-term survival was comparable between the groups. Conclusion The aetiology of heart failure did not impact short-term or long-term clinical outcomes after VAD surgery. Multicentre registry data are necessary to substantiate these findings.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Ivanov, Borko UNSPECIFIED UNSPECIFIED UNSPECIFIED Djordjevic, Ilija UNSPECIFIED orcid.org/0000-0002-5810-8626 UNSPECIFIED Sabashnikov, Anton UNSPECIFIED UNSPECIFIED UNSPECIFIED Sindhu, Dirk UNSPECIFIED UNSPECIFIED UNSPECIFIED Hink, Stephan UNSPECIFIED UNSPECIFIED UNSPECIFIED Eghbalzadeh, Kaveh UNSPECIFIED UNSPECIFIED UNSPECIFIED Gerfer, Stephen UNSPECIFIED orcid.org/0000-0002-6568-6766 UNSPECIFIED Gaisendrees, Christopher UNSPECIFIED UNSPECIFIED UNSPECIFIED Schlachtenberger, Georg UNSPECIFIED orcid.org/0000-0001-7118-8432 UNSPECIFIED Rustenbach, Christian UNSPECIFIED orcid.org/0000-0003-2178-8397 UNSPECIFIED Seuthe, Katharina UNSPECIFIED UNSPECIFIED UNSPECIFIED Regnier, Kuhn UNSPECIFIED UNSPECIFIED UNSPECIFIED Mader, Navid UNSPECIFIED UNSPECIFIED UNSPECIFIED Pfister, Roman UNSPECIFIED UNSPECIFIED UNSPECIFIED Zeriouh, Mohamed UNSPECIFIED UNSPECIFIED UNSPECIFIED Rahmanian, Parwis UNSPECIFIED UNSPECIFIED UNSPECIFIED Wahlers, Thorsten UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-664748
DOI:	10.1016/j.hlc.2021.08.017
Journal or Publication Title:	Heart Lung Circ.
Volume:	31
Number:	3
Page Range:	S. 383 - 390
Date:	2022
Publisher:	ELSEVIER SCIENCE INC
Place of Publication:	NEW YORK
ISSN:	1444-2892
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language HEART-FAILURE; THERAPY; SECONDARY; ETIOLOGY; OUTCOMES Multiple languages Cardiac & Cardiovascular Systems Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/66474