Universität zu Köln

Journal Article

Buchholz, Christian J., Friedel, Thorsten and Buening, Hildegard (2015). Surface-Engineered Viral Vectors for Selective and Cell Type-Specific Gene Delivery. Trends Biotechnol., 33 (12). S. 777 - 791. LONDON: ELSEVIER SCIENCE LONDON. ISSN 1879-3096

Buening, Hildegard (2014). Redirecting T cells by chimeric antigen receptors. Hum. Gene Ther., 25 (11). S. A2 - 2. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1557-7422

Buening, Hildegard, Huber, Anke, Zhang, Liang, Meumann, Nadja and Hacker, Ulrich ORCID: 0000-0002-3253-8206 (2015). Engineering the AAV capsid to optimize vector-host-interactions. Curr. Opin. Pharmacol., 24. S. 94 - 105. OXFORD: ELSEVIER SCI LTD. ISSN 1471-4973

Chamorro, Cristina, Mencia, Angeles, Almarza, David, Duarte, Blanca, Buening, Hildegard, Sallach, Jessica, Hausser, Ingrid, Del Rio, Marcela, Larcher, Fernando ORCID: 0000-0002-6771-3561 and Murillas, Rodolfo (2016). Gene Editing for the Efficient Correction of a Recurrent COL7A1 Mutation in Recessive Dystrophic Epidermolysis Bullosa Keratinocytes. Mol. Ther.-Nucl. Acids, 5. S. 1 - 14. NEW YORK: NATURE PUBLISHING GROUP. ISSN 2162-2531

Coutelle, Oliver, Buening, Hildegard, Pluetschow, Annette, Fuchs, Michael, Escalona-Espinosa, Laura, Engert, Andreas and Hacker, Ulrich ORCID: 0000-0002-3253-8206 (2014). Prognostic Serum Cytokines in Classical Hodgkin Lymphoma-Letter. Clin. Cancer Res., 20 (24). S. 6633 - 6634. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Franzoso, Francesca D., Seyffert, Michael ORCID: 0000-0001-7483-2430, Vogel, Rebecca, Yakimovich, Artur, Pereira, Bruna de Andrade, Meier, Anita F., Sutter, Sereina O., Tobler, Kurt, Vogt, Bernd, Greber, Urs F., Buening, Hildegard, Ackermann, Mathias and Fraefel, Cornel ORCID: 0000-0001-7221-6706 (2017). Cell Cycle-Dependent Expression of Adeno-Associated Virus 2 (AAV2) Rep in Coinfections with Herpes Simplex Virus 1 (HSV-1) Gives Rise to a Mosaic of Cells Replicating either AAV2 or HSV-1. J. Virol., 91 (15). WASHINGTON: AMER SOC MICROBIOLOGY. ISSN 1098-5514

Fuchsluger, Thomas Armin, Schmeer, Marco, Schleef, Martin, Schnoedt, Maria, Buening, Hildegard, Kruse, Friedrich E. and Gruenert, Anja Katharina (2017). A new tool for transfection of corneal endothelial cells: minicircle-based AAV-vectors. Invest. Ophthalmol. Vis. Sci., 58 (8). ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC. ISSN 1552-5783

Grimm, Dirk and Buening, Hildegard (2017). Small But Increasingly Mighty: Latest Advances in AAV Vector Research, Design, and Evolution. Hum. Gene Ther., 28 (11). S. 1075 - 1087. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1557-7422

Gruenert, Anja Katharina, Buening, Hildegard, Schnoedt, Maria, Schmeer, Marco, Schleef, Martin, Kruse, Friedrich E. and Fuchsluger, Thomas Armin (2015). Self-complementary AAV2 vectors improve transduction efficiency of corneal endothelial cells. Invest. Ophthalmol. Vis. Sci., 56 (7). ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC. ISSN 1552-5783

Hacker, Ulrich T., Escalona-Espinosa, Laura, Consalvo, Nicola, Goede, Valentin, Schiffmann, Lars, Scherer, Stefan J., Hedge, Priti, Van Cutsem, Eric, Coutelle, Oliver and Buening, Hildegard (2016). Evaluation of Angiopoietin-2 as a biomarker in gastric cancer: results from the randomised phase III AVAGAST trial. Br. J. Cancer, 114 (8). S. 855 - 863. LONDON: NATURE PUBLISHING GROUP. ISSN 1532-1827

Hagedorn, Claudia, Schnoedt-Fuchs, Maria, Boehme, Philip, Abdelrazik, Heba, Lipps, Hans J. and Buening, Hildegard (2017). S/MAR Element Facilitates Episomal Long-Term Persistence of Adeno-Associated Virus Vector Genomes in Proliferating Cells. Hum. Gene Ther., 28 (12). S. 1169 - 1180. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1557-7422

Hoerner, Maximilian, Kaufmann, Beate, Cotugno, Gabriella, Wiedtke, Ellen, Buening, Hildegard, Grimm, Dirk and Weber, Wilfried ORCID: 0000-0003-4340-4446 (2014). A chemical switch for controlling viral infectivity. Chem. Commun., 50 (71). S. 10319 - 10323. CAMBRIDGE: ROYAL SOC CHEMISTRY. ISSN 1364-548X

Hoesel, Marianna, Huber, Anke, Bohlen, Susanne, Lucifora, Julie, Ronzitti, Giuseppe, Puzzo, Francesco, Boisgerault, Florence, Hacker, Ulrich T., Kwanten, Wilhelmus J., Kloeting, Nora, Blueher, Matthias, Gluschko, Alexander, Schramm, Michael, Utermoehlen, Olaf, Bloch, Wilhelm, Mingozzi, Federico, Krut, Oleg and Buening, Hildegard (2017). Autophagy Determines Efficiency of Liver-Directed Gene Therapy With Adeno-Associated Viral Vectors. Hepatology, 66 (1). S. 252 - 266. HOBOKEN: WILEY. ISSN 1527-3350

Hoesel, Marianna, Lucifora, Julie, Michler, Thomas ORCID: 0000-0002-4174-3316, Holz, Gisela, Gruffaz, Marion, Stahnke, Stephanie, Zoulim, Fabien ORCID: 0000-0002-2245-0083, Durantel, David ORCID: 0000-0002-9226-3419, Heikenwalder, Mathias, Nierhoff, Dirk, Millet, Rachel, Salvetti, Anna ORCID: 0000-0003-2007-8350, Protzer, Ulrike ORCID: 0000-0002-9421-1911 and Buening, Hildegard (2014). Hepatitis B Virus Infection Enhances Susceptibility Toward Adeno-Associated Viral Vector Transduction In Vitro and In Vivo. Hepatology, 59 (6). S. 2110 - 2121. HOBOKEN: WILEY-BLACKWELL. ISSN 1527-3350

Hoesel, Marianna, Quasdorff, Maria, Ringelhan, Marc ORCID: 0000-0003-3131-5657, Kashkar, Hamid, Debey-Pascher, Svenja, Sprinzl, Martin F., Bockmann, Jan-Hendrik, Arzberger, Silke, Webb, Dennis, von Olshausen, Gesa ORCID: 0000-0001-8145-0414, Weber, Achim ORCID: 0000-0003-0073-3637, Schultze, Joachim L., Buening, Hildegard, Heikenwalder, Mathias and Protzer, Ulrike ORCID: 0000-0002-9421-1911 (2017). Hepatitis B Virus Activates Signal Transducer and Activator of Transcription 3 Supporting Hepatocyte Survival and Virus Replication. Cell. Mol. Gastroenterol. Hepatol., 4 (3). S. 339 - 364. SAN DIEGO: ELSEVIER INC. ISSN 2352-345X

Horwitz, Joshua A., Halper-Stromberg, Ariel, Mouquet, Hugo ORCID: 0000-0002-4230-610X, Gitlin, Alexander D., Tretiakova, Anna, Eisenreich, Thomas R., Malbec, Marine, Gravemann, Sophia, Billerbeck, Eva, Dorner, Marcus ORCID: 0000-0003-0321-4226, Buening, Hildegard, Schwartz, Olivier, Knops, Elena, Kaiser, Rolf, Seaman, Michael S., Wilson, James M., Rice, Charles M., Ploss, Alexander ORCID: 0000-0001-9322-7252, Bjorkman, Pamela J., Klein, Florian and Nussenzweig, Michel C. (2013). HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice. Proc. Natl. Acad. Sci. U. S. A., 110 (41). S. 16538 - 16544. WASHINGTON: NATL ACAD SCIENCES. ISSN 0027-8424

Kallendrusch, Sonja, Schopow, Nikolas, Stadler, Sonja C., Buening, Hildegard and Hacker, Ulrich T. (2016). Adeno-Associated Viral Vectors Transduce Mature Human Adipocytes in Three-Dimensional Slice Cultures. Hum. Gene Ther. Methods, 27 (5). S. 171 - 174. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1946-6544

Kaufmann, Kerstin B. ORCID: 0000-0001-5013-6123, Buening, Hildegard, Galy, Anne, Schambach, Axel and Grez, Manuel (2013). Gene therapy on the move. EMBO Mol. Med., 5 (11). S. 1642 - 1662. HOBOKEN: WILEY. ISSN 1757-4684

Kleinlogel, Sonja, Hulliger, Elmar, van Wyk, Michiel, David, Anand, Odenthal, Margarete and Buening, Hildegard (2018). Evolution of recombinant adeno-associated viral vectors with favourable retinal penetration properties. Invest. Ophthalmol. Vis. Sci., 59 (9). ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC. ISSN 1552-5783

Maersch, Stephan, Huber, Anke, Hallek, Michael, Buening, Hildegard and Perabo, Luca (2010). A Novel Directed Evolution Method to Enhance Cell-Type Specificity of Adeno-Associated Virus Vectors. Comb. Chem. High Throughput Screen, 13 (9). S. 807 - 813. SHARJAH: BENTHAM SCIENCE PUBL LTD. ISSN 1875-5402

Meumann, Nadja, Schmithals, Christian, Elenschneider, Leroy, Hansen, Tanja, Balakrishnan, Asha, Hu, Qingluan, Hook, Sebastian, Schmitz, Jessica ORCID: 0000-0001-9843-7339, Braesen, Jan Hinrich, Franke, Ann-Christin, Olarewaju, Olaniyi, Brandenberger, Christina, Talbot, Steven R., Fangmann, Josef, Hacker, Ulrich T., Odenthal, Margarete ORCID: 0000-0002-2424-0960, Ott, Michael, Piiper, Albrecht and Buening, Hildegard (2022). Hepatocellular Carcinoma Is a Natural Target for Adeno-Associated Virus (AAV) 2 Vectors. Cancers, 14 (2). BASEL: MDPI. ISSN 2072-6694

Michalakis, Stylianos ORCID: 0000-0001-5092-9238, Muehlfriedel, Regine, Tanimoto, Naoyuki, Krishnamoorthy, Vidhyasankar, Koch, Susanne ORCID: 0000-0001-9966-113X, Fischer, M. Dominik, Becirovic, Elvir ORCID: 0000-0001-8801-0649, Bai, Lin, Huber, Gesine, Beck, Susanne C., Fahl, Edda, Buening, Hildegard, Paquet-Durand, Francois ORCID: 0000-0001-7355-5742, Zong, Xiangang, Gollisch, Tim ORCID: 0000-0003-3998-533X, Biel, Martin and Seeliger, Mathias W. (2010). Restoration of Cone Vision in the CNGA3(-/-) Mouse Model of Congenital Complete Lack of Cone Photoreceptor Function. Mol. Ther., 18 (12). S. 2057 - 2064. CAMBRIDGE: CELL PRESS. ISSN 1525-0024

Millet, Rachel, Jolinon, Nelly, Berger, Gregory, Cimarelli, Andrea, Greco, Anna, Bertrand, Pascale, Odenthal, Margarete, Buening, Hildegard and Salvetti, Anna ORCID: 0000-0003-2007-8350 (2015). Impact of the MRN Complex on Adeno-Associated Virus Integration and Replication during Coinfection with Herpes Simplex Virus 1. J. Virol., 89 (13). S. 6824 - 6835. WASHINGTON: AMER SOC MICROBIOLOGY. ISSN 1098-5514

Mingozzi, Federico and Buening, Hildegard (2015). Adeno-associated viral vectors at the frontier between tolerance and immunity. Front. Immunol., 6. LAUSANNE: FRONTIERS RESEARCH FOUNDATION. ISSN 1664-3224

Mingozzi, Federico and Buening, Hildegard (2015). Adeno-associated viral vectors at the frontier between tolerance and immunity. Front. Immunol., 6. LAUSANNE: FRONTIERS RESEARCH FOUNDATION. ISSN 1664-3224

Muench, Robert C., Muth, Anke, Muik, Alexander, Friedel, Thorsten, Schmatz, Julia, Dreier, Birgit, Trkola, Alexandra ORCID: 0000-0003-1013-876X, Plueckthun, Andreas, Buening, Hildegard and Buchholz, Christian J. (2015). Off-target-free gene delivery by affinity-purified receptor-targeted viral vectors. Nat. Commun., 6. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Muench, Robert C., Rasbach, Anke, Muik, Alexander, Friedel, Thorsten, Kalicki, Julia, Dreier, Birgit, Trkola, Alexandra, Plueckthun, Andreas, Buening, Hildegard and Buchholz, Christian J. (2014). Off-target-free gene delivery to clinically relevant cell types by receptor-targeted adeno-associated viral vectors. Hum. Gene Ther., 25 (11). S. A53 - 1. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1557-7422

Neerincx, Andreas, Jakobshagen, Kristin, Utermoehlen, Olaf, Buening, Hildegard, Steimle, Viktor and Kufer, Thomas A. (2014). The N-Terminal Domain of NLRC5 Confers Transcriptional Activity for MHC Class I and II Gene Expression. J. Immunol., 193 (6). S. 3090 - 3101. BETHESDA: AMER ASSOC IMMUNOLOGISTS. ISSN 1550-6606

Nicolas, Armel, Jolinon, Nelly, Alazard-Dany, Nathalie, Barateau, Veronique, Epstein, Alberto L., Greco, Anna, Buening, Hildegard and Salvetti, Anna ORCID: 0000-0003-2007-8350 (2012). Factors influencing helper-independent adeno-associated virus replication. Virology, 432 (1). S. 1 - 10. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE. ISSN 0042-6822

Pradas-Juni, Marta, Hansmeier, Nils R., Link, Jenny C., Schmidt, Elena ORCID: 0000-0003-0829-1423, Larsen, Bjork Ditlev, Klemm, Paul ORCID: 0000-0002-5985-1737, Meola, Nicola, Topel, Hande ORCID: 0000-0001-5743-4019, Loureiro, Rute, Dhaouadi, Ines ORCID: 0000-0002-2762-6500, Kiefer, Christoph A., Schwarzer, Robin, Khani, Sajjad, Oliverio, Matteo, Awazawa, Motoharu, Frommolt, Peter ORCID: 0000-0002-1966-8014, Heeren, Joerg, Scheja, Ludger, Heine, Markus, Dieterich, Christoph, Buening, Hildegard, Yang, Ling, Cao, Haiming, De Jesus, Dario F., Kulkarni, Rohit N., Zevnik, Branko ORCID: 0000-0001-7845-9522, Troeder, Simon E., Knippschild, Uwe, Edwards, Peter A., Lee, Richard G., Yamamoto, Masayuki, Ulitsky, Igor, Fernandez-Rebollo, Eduardo, Vallim, Thomas Q. de Aguiar and Kornfeld, Jan-Wilhelm ORCID: 0000-0002-6802-4442 (2020). A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism. Nat. Commun., 11 (1). LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Rasbach, Anke, Muench, Robert C., Kalicki, Julia, Buening, Hildegard and Buchholz, Christian J. (2014). Second Generation Entry Targeted AAV Vectors: Reduced Off-Targeting, Flexibility in Receptor Choice and Enhanced Gene Delivery. Mol. Ther., 22. S. S109 - 1. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1525-0024

Rode, Laura, Baer, Christian, Gross, Sonja, Rossi, Axel, Meumann, Nadja, Viereck, Janika, Abbas, Naisam, Xiao, Ke, Riedel, Isabelle, Gietz, Anika, Zimmer, Karina, Odenthal, Margarete, Buening, Hildegard and Thum, Thomas (2022). AAV capsid engineering identified two novel variants with improved in vivo tropism for cardiomyocytes. Mol. Ther., 30 (12). S. 3601 - 3619. CAMBRIDGE: CELL PRESS. ISSN 1525-0024

Rodriguez-Marquez, Esther, Meumann, Nadja and Buening, Hildegard . Adeno-associated virus (AAV) capsid engineering in liver-directed gene therapy. Expert Opin. Biol. Ther.. ABINGDON: TAYLOR & FRANCIS LTD. ISSN 1744-7682

Rossi, Axel, Dupaty, Lea, Aillot, Ludovic, Zhang, Liang, Gallien, Celia, Hallek, Michael, Odenthal, Margarete, Adriouch, Sahil, Salvetti, Anna ORCID: 0000-0003-2007-8350 and Buening, Hildegard (2019). Vector uncoating limits adenoassociated viral vector-mediated transduction of human dendritic cells and vector immunogenicity. Sci Rep, 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322

Rybniker, Jan, Nowag, Angela, Janicki, Hanna, Demant, Kai, Hartmann, Pia and Buening, Hildegard (2012). Incorporation of Antigens into Viral Capsids Augments Immunogenicity of Adeno-Associated Virus Vector-Based Vaccines. J. Virol., 86 (24). S. 13800 - 13805. WASHINGTON: AMER SOC MICROBIOLOGY. ISSN 1098-5514

Sallach, Jessica, Di Pasquale, Giovanni, Larcher, Fernando ORCID: 0000-0002-6771-3561, Niehoff, Nadine, Ruebsam, Matthias, Huber, Anke, Chiorini, Jay, Almarza, David, Eming, Sabine A., Ulus, Hikmet, Nishimura, Stephen, Hacker, Ulrich T., Hallek, Michael, Niessen, Carien M. and Buening, Hildegard (2014). Tropism-modified AAV Vectors Overcome Barriers to Successful Cutaneous Therapy. Mol. Ther., 22 (5). S. 929 - 940. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1525-0024

Schleef, Martin, Schmeer, Marco, Schnoedt, Maria, Fuchsluger, Thomas and Buening, Hildegard (2014). Minicircle DNA derived AAV. Hum. Gene Ther., 25 (11). S. A86 - 1. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1557-7422

Schmeer, Marco, Buchholz, Tatjana, Schleef, Martin, Schnoedt, Maria, Gruenert, Anja, Shankar, Ram, Fuchsluger, Thomas and Buening, Hildegard (2016). Production of Safe and Efficient AAV Vectors Using Minicircle DNA. Mol. Ther., 24. S. S123 - 1. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1525-0024

Schmeer, Marco, Schleef, Martin, Schnoedt, Maria, Gruenert, Anja, Selvamani, Ram, Fuchsluger, Thomas and Buening, Hildegard (2015). Production of safe and efficient AAV vectors using minicircle DNA. Hum. Gene Ther., 26 (9). S. A12 - 1. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1557-7422

Schnoedt, Maria and Buening, Hildegard (2017). Improving the Quality of Adeno-Associated Viral Vector Preparations: The Challenge of Product-Related Impurities. Hum. Gene Ther. Methods, 28 (3). S. 101 - 109. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1946-6544

Schnoedt, Maria, Schmeer, Marco, Kracher, Barbara, Kruesemann, Christa, Espinosa, Laura Escalona, Gruenert, Anja, Fuchsluger, Thomas, Rischmueller, Anja, Schleef, Martin and Buening, Hildegard (2016). DNA Minicircle Technology Improves Purity of Adeno-associated Viral Vector Preparations. Mol. Ther.-Nucl. Acids, 5. CAMBRIDGE: CELL PRESS. ISSN 2162-2531

Seyffert, Michael ORCID: 0000-0001-7483-2430, Glauser, Daniel L., Schraner, Elisabeth M., de Oliveira, Anna-Paula, Mansilla-Soto, Jorge, Vogt, Bernd, Buening, Hildegard, Linden, R. Michael, Ackermann, Mathias and Fraefel, Cornel ORCID: 0000-0001-7221-6706 (2017). Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus Replication. PLoS One, 12 (1). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

Seyffert, Michael ORCID: 0000-0001-7483-2430, Glauser, Daniel L., Tobler, Kurt, Georgiev, Oleg, Vogel, Rebecca, Vogt, Bernd, Agundez, Leticia, Linden, Michael, Buening, Hildegard, Ackermann, Mathias and Fraefel, Cornel ORCID: 0000-0001-7221-6706 (2015). Adeno-Associated Virus Type 2 Rep68 Can Bind to Consensus Rep-Binding Sites on the Herpes Simplex Virus 1 Genome. J. Virol., 89 (21). S. 11150 - 11159. WASHINGTON: AMER SOC MICROBIOLOGY. ISSN 1098-5514

Tovar, Sulay ORCID: 0000-0001-7813-6520, Paeger, Lars ORCID: 0000-0001-8716-3483, Hess, Simon, Morgan, Donald A., Hausen, A. Christine, Broenneke, Hella S., Hampel, Brigitte, Ackermann, P. Justus, Evers, Nadine, Buening, Hildegard, Wunderlich, F. Thomas, Rahmouni, Kamal ORCID: 0000-0001-5136-6748, Kloppenburg, Peter and Bruening, Jens C. (2013). K-ATP-Channel-Dependent Regulation of Catecholaminergic Neurons Controls BAT Sympathetic Nerve Activity and Energy Homeostasis. Cell Metab., 18 (3). S. 445 - 456. CAMBRIDGE: CELL PRESS. ISSN 1932-7420

Trible, Ronald, Palesch, David, Gravemann, Sophia, Buening, Hildegard, Kirchhoff, Frank ORCID: 0000-0002-7052-2360 and Silvestri, Guido (2014). ADMINISTRATION OF AAV-BASED ANTI-HIV IMMUNOADHESINS IN SHIV-INFECTED RHESUS MACAQUES. J. Med. Primatol., 43 (5). S. 400 - 401. HOBOKEN: WILEY-BLACKWELL. ISSN 1600-0684

Vogt, Annabelle, Sievers, Elisabeth, Lukacs-Kornek, Veronika, Decker, Georges, Raskopf, Esther, Meumann, Nadja, Buening, Hildegard, Sauerbruch, Tilman, Strassburg, Christian P., Schmidt-Wolf, Ingo G. H. and Gonzalez-Carmona, Maria A. (2014). Improving immunotherapy of hepatocellular carcinoma (HCC) using dendritic cells (DC) engineered to express IL-12 in vivo. Liver Int., 34 (3). S. 447 - 462. HOBOKEN: WILEY-BLACKWELL. ISSN 1478-3231

Zhang, Li-Ang, Koitzsch, Ulrike, Odenthal, Margarete and Buening, Hildegard (2014). Capsid-engineering overcomes barriers toward endothelial cell transduction. Hum. Gene Ther., 25 (11). S. A53 - 1. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1557-7422