Universität zu Köln

Metze, Clemens ORCID: 0000-0001-8980-4598, Zweck, Elric, Iliadis, Christos ORCID: 0000-0001-7655-8500, Körber, Maria Isabel ORCID: 0000-0001-9073-9279, Schäfer, Matthieu ORCID: 0000-0003-1875-1163, Westenfeld, Ralf, Polzin, Amin, Halbach, Marcel ORCID: 0000-0002-6361-5825, Baldus, Stephan ORCID: 0000-0001-8259-1737 and Pfister, Roman ORCID: 0000-0002-4358-5008 (2025). A Simplified Frailty Measure Improves Risk Stratification in Patients Undergoing Percutaneous Mitral Valve Repair. Journal of Cachexia, Sarcopenia and Muscle, 16 (6). pp. 1-13. Wiley. ISSN 2190-5991

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Abstract

[Artikel-Nr.: e70138] We assessed the Fried frailty criteria in 524 patients undergoing percutaneous mitral valve repair and derived a simplified frailty measure comprising self‐reported exhaustion and gait speed, which was significantly associated with 1‐year mortality and mortality or heart failure hospitalization independently of clinical risk factors and the well‐established MitraScore. Additionally, the simplified frailty measure significantly improved risk prediction of the MitraScore. These findings provide first evidence supporting the assessment of frailty measures as part of the decision‐making process and multiparametric risk scores in patients with severe mitral regurgitation.

Item Type:	Article
Creators:	Creators Email ORCID ORCID Put Code Metze, Clemens UNSPECIFIED https://orcid.org/0000-0001-8980-4598 UNSPECIFIED Zweck, Elric UNSPECIFIED UNSPECIFIED UNSPECIFIED Iliadis, Christos UNSPECIFIED https://orcid.org/0000-0001-7655-8500 UNSPECIFIED Körber, Maria Isabel UNSPECIFIED https://orcid.org/0000-0001-9073-9279 UNSPECIFIED Schäfer, Matthieu UNSPECIFIED https://orcid.org/0000-0003-1875-1163 UNSPECIFIED Westenfeld, Ralf UNSPECIFIED UNSPECIFIED UNSPECIFIED Polzin, Amin UNSPECIFIED UNSPECIFIED UNSPECIFIED Halbach, Marcel UNSPECIFIED https://orcid.org/0000-0002-6361-5825 UNSPECIFIED Baldus, Stephan UNSPECIFIED https://orcid.org/0000-0001-8259-1737 UNSPECIFIED Pfister, Roman UNSPECIFIED https://orcid.org/0000-0002-4358-5008 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-801661
Identification Number:	10.1002/jcsm.70138
Journal or Publication Title:	Journal of Cachexia, Sarcopenia and Muscle
Volume:	16
Number:	6
Page Range:	pp. 1-13
Number of Pages:	13
Date:	1 December 2025
Publisher:	Wiley
ISSN:	2190-5991
Language:	English
Faculty:	Faculty of Medicine
Divisions:	Faculty of Medicine > Innere Medizin > Klinik III für Innere Medizin - Kardiologie, Pneumologie, Angiologie und internistische Intensivmedizin
Subjects:	Medical sciences Medicine
Uncontrolled Keywords:	Keywords Language frailty ; MitraClip ; percutaneous mitral valve repair ; risk score English
['eprint_fieldname_oa_funders' not defined]:	Publikationsfonds UzK
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/80166