Universität zu Köln

Klingenstein, Annemarie, Samel, Christina, Garip-Kuebler, Aylin, Miller, Christina, Liegl, Raffael G., Priglinger, Siegfried G. and Foerster, Paul I. . The national comprehensive cancer network distress thermometer as a screening tool for the evaluation of quality of life in uveal melanoma patients. Acta Ophthalmol.. HOBOKEN: WILEY. ISSN 1755-3768

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Abstract

Purpose To assess quality of life (QoL) status via the National Comprehensive Cancer Network (NCCN) distress thermometer as a psychooncological screening tool in uveal melanoma patients. Methods One hundred and six consecutive patients suffering from uveal melanoma completed the distress thermometer between 04/2018 and 12/2018. Practical, emotional, family concerned, spiritual, physical and overall distress levels, distribution of distress and subgroup analyses defining groups of potential high distress levels in need of intervention were assessed. Descriptive statistics, cross-tabulations, chi-square and Fisher's exact test as well as correlation coefficients (Spearman's rho) and receiver operating characteristic (ROC) were used for analysis. Results Patients with higher T-category had significantly more emotional problems and spiritual concerns (p = 0.046 and p = 0.023, respectively). Female patients accounted for higher rates of physical issues (p = 0.034). Lower best corrected visual acuity (BCVA) was correlated with higher distress levels (p = 0.037). Patients resulting in loss of BCVA of >= 3 lines reported higher distress levels (p = 0.029). A distress threshold of 5 on the basis of ROC analysis showed a corresponding sensitivity of 100% and specificity of 76%. Conclusion The NCCN distress thermometer could be integrated well into our clinical routine and proved to be a rapid, yet sensible screening tool for emotional and physical distress in patients with uveal melanoma. Special attention should be paid to patients with higher T-category and patients resulting in lower levels of BCVA. As in patients with different tumour entities, the established distress threshold of >= 5 proposing intervention proved to be adequate for uveal melanoma patients.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Klingenstein, Annemarie UNSPECIFIED UNSPECIFIED UNSPECIFIED Samel, Christina UNSPECIFIED UNSPECIFIED UNSPECIFIED Garip-Kuebler, Aylin UNSPECIFIED UNSPECIFIED UNSPECIFIED Miller, Christina UNSPECIFIED UNSPECIFIED UNSPECIFIED Liegl, Raffael G. UNSPECIFIED UNSPECIFIED UNSPECIFIED Priglinger, Siegfried G. UNSPECIFIED UNSPECIFIED UNSPECIFIED Foerster, Paul I. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-130357
DOI:	10.1111/aos.14277
Journal or Publication Title:	Acta Ophthalmol.
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1755-3768
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language FOLLOW-UP; PSYCHOLOGICAL REACTIONS; EUROPEAN ORGANIZATION; CHOROIDAL MELANOMA; QUESTIONNAIRE; ENUCLEATION; DEPRESSION; VALIDATION; THERAPY Multiple languages Ophthalmology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/13035