Universität zu Köln

Loeser, Johannes, Schwemmer, Julian, Gostian, Antoniu-Oreste, Gostian, Magdalena, Bachmann, Bjoern, Cursiefen, Claus and Heindl, Ludwig M. (2019). Postoperative pain following Descemet membrane endothelial keratoplasty (DMEK): a prospective study. Graefes Arch. Clin. Exp. Ophthalmol., 257 (10). S. 2203 - 2212. NEW YORK: SPRINGER. ISSN 1435-702X

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Abstract

Purpose To evaluate postoperative pain following Descemet membrane endothelial keratoplasty (DMEK). Methods Seventy-one patients completed perioperatively (day before surgery, day of surgery, 1st, 2nd, and 3rd day after surgery) four different questionnaires (a hospital internal protocol, QUIPS, PainDETECT (R), and SF36) regarding their pain and other clinical parameters such as constipation, tiredness, vertigo, sleep disorders, concentration disorders, nausea, and emesis. All standardised questionnaires were evaluated to quantify average pain intensity as well as maximum pain intensity (NRS, 0 [no pain] to 10 [maximal pain], respectively). Analgesic treatment and intraocular pressure (IOP) during the perioperative stay were documented. Results Mean average pain intensity was 0.70 +/- 1.64 before surgery, 1.97 +/- 2.05 on the day of surgery, 1.39 +/- 1.68 on day 1, 0.87 +/- 1.36 on day 2, and 0.81 +/- 1.24 on day 3 after surgery. Maximum pain intensity was 0.65 +/- 1.81 before surgery, 3.35 +/- 2.98 on the day of surgery, 2.68 +/- 2.99 on day 1, 1.49 +/- 2.15 on day 2, and 1.26 +/- 2.02 on day 3 after surgery. During the first three postoperative days, over 90% of the patients stated no or well tolerable pain. Eighty-three percent had postoperatively no need for analgesics at all. On the first two postoperative days, maximum IOP correlated significantly with reported increased maximum pain intensity (p = 0.043 and p = 0.029, respectively). All patients had very little problems with constipation, tiredness, vertigo, sleep disorder, concentration disorders, nausea, and emesis. Conclusions DMEK is associated with low postoperative pain intensity. Strong pain increase may indicate IOP elevation and should be further investigated and treated.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Loeser, Johannes UNSPECIFIED UNSPECIFIED UNSPECIFIED Schwemmer, Julian UNSPECIFIED UNSPECIFIED UNSPECIFIED Gostian, Antoniu-Oreste UNSPECIFIED UNSPECIFIED UNSPECIFIED Gostian, Magdalena UNSPECIFIED UNSPECIFIED UNSPECIFIED Bachmann, Bjoern UNSPECIFIED UNSPECIFIED UNSPECIFIED Cursiefen, Claus UNSPECIFIED UNSPECIFIED UNSPECIFIED Heindl, Ludwig M. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-131962
DOI:	10.1007/s00417-019-04437-5
Journal or Publication Title:	Graefes Arch. Clin. Exp. Ophthalmol.
Volume:	257
Number:	10
Page Range:	S. 2203 - 2212
Date:	2019
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1435-702X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PERSISTENT POSTSURGICAL PAIN; SPLIT CORNEA TRANSPLANTATION; NEUROPATHIC COMPONENT; QUESTIONNAIRE; PREVALENCE; PAINDETECT; SURGERY; 1ST; AIR Multiple languages Ophthalmology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/13196