Canepa, Marco, Franssen, Frits M. E., Olschewski, Horst ORCID: 0000-0002-2834-7466, Lainscak, Mitja, Boehm, Michael, Tavazzi, Luigi and Rosenkranz, Stephan (2019). Diagnostic and Therapeutic Gaps in Patients With Heart Failure and Chronic Obstructive Pulmonary Disease. JACC-Heart Fail., 7 (10). S. 823 - 834. OXFORD: ELSEVIER SCI LTD. ISSN 2213-1787

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Abstract

Heart failure (HF) and chronic obstructive pulmonary disease (COPD) coincide in a significant number of patients. Recent population-based registries suggest that spirometry is largely underused in patients with HF to diagnose comorbid COPD and that patients with COPD frequently do not receive the recommended beta-blocker (BB) treatment. This state-of-the-art review summarizes: 1) current challenges in the implementation of recommended spirometry for COPD diagnosis in patients with HF; and 2) current underuse and underdosing of BBs in patients with HF and COPD despite guideline recommendations. Open issues in the therapeutic management of patients with HF and COPD are discussed in the third section, including the use of the nonselective BB carvedilol, target BB doses in patients with HF and COPD, BB and bronchodilator management during HF hospitalization with and without COPD exacerbation, and the use of BBs in patients with COPD with right HF or free from cardiovascular disease. The whole scenario described herein advocates for a bipartisan initiative to drive immediate attention to the translation of guideline recommendations into clinical practice for patients with HF with co-occurring COPD. (C) 2019 by the American College of Cardiology Foundation.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Canepa, MarcoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Franssen, Frits M. E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Olschewski, HorstUNSPECIFIEDorcid.org/0000-0002-2834-7466UNSPECIFIED
Lainscak, MitjaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Boehm, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tavazzi, LuigiUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rosenkranz, StephanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-132851
DOI: 10.1016/j.jchf.2019.05.009
Journal or Publication Title: JACC-Heart Fail.
Volume: 7
Number: 10
Page Range: S. 823 - 834
Date: 2019
Publisher: ELSEVIER SCI LTD
Place of Publication: OXFORD
ISSN: 2213-1787
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
2013 ACCF/AHA GUIDELINE; BETA-BLOCKERS; SYSTOLIC DYSFUNCTION; PROGNOSTIC IMPACT; EUROPEAN-SOCIETY; LUNG-DISEASE; MORTALITY; OUTCOMES; RISK; ASSOCIATIONMultiple languages
Cardiac & Cardiovascular SystemsMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/13285

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