Universität zu Köln

Salokangas, Raimo K. R., Patterson, Paul ORCID: 0000-0003-3310-8635, Hietala, Jarmo ORCID: 0000-0002-3179-6780, Heinimaa, Markus, From, Tiina, Ilonen, Tuula, von Reventlow, Heinrich Graf, Schultze-Lutter, Frauke, Juckel, Georg, Linszen, Don, Dingemans, Peter, Birchwood, Max, Klosterkoetter, Joachim, Ruhrmann, Stephan ORCID: 0000-0002-6022-2364, McGorry, Patrick D., McGlashan, Thomas H. and Knapp, Martin (2019). Childhood adversity predicts persistence of suicidal thoughts differently in females and males at clinical high-risk patients of psychosis. Results of the EPOS project. Early Interv. Psychiatry, 13 (4). S. 935 - 943. HOBOKEN: WILEY. ISSN 1751-7893

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Abstract

Aim Depression and suicidal ideation (SUI) and behaviour are more prevalent in females than males, and common in clinical high-risk (CHR) patients. Childhood adversities and trauma (CAT) are associated with adult depression and SUI. The role of gender as a moderator and depression as a mediator for the effect of CAT on SUI has not been explored in CHR patients. Methods In all, 245 young help-seeking CHR patients were assessed for SUI (thoughts of killing themselves) with the Beck Depression Inventory at baseline, 9-month and 18-month follow-ups. At baseline, clinical depression was assessed by the Structured Clinical Interview for DSM-IV (SCID-I), and CAT by the Trauma and Distress Scale (TADS) which includes the five domains of emotional, physical and sexual abuse, emotional and physical neglect. Results CAT total and all domains except physical neglect predicted SUI over the study period. The effect of CAT on SUI was mediated via clinical depression and concurrent depression symptoms differently for females and males. In females, the effect of emotional abuse and neglect on SUI was mediated via baseline depression. In males, emotional and physical abuse had a direct effect on SUI, and the effect of sexual abuse and emotional neglect was partly mediated via concurrent depression symptoms. Conclusions For CHR females, the effect of CAT on adult SUI is mediated via depression, while for males, CAT and its domains have mainly direct effects in maintaining SUI. These gender differences should be taken into account when treating CHR patients with SUI.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Salokangas, Raimo K. R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Patterson, Paul UNSPECIFIED orcid.org/0000-0003-3310-8635 UNSPECIFIED Hietala, Jarmo UNSPECIFIED orcid.org/0000-0002-3179-6780 UNSPECIFIED Heinimaa, Markus UNSPECIFIED UNSPECIFIED UNSPECIFIED From, Tiina UNSPECIFIED UNSPECIFIED UNSPECIFIED Ilonen, Tuula UNSPECIFIED UNSPECIFIED UNSPECIFIED von Reventlow, Heinrich Graf UNSPECIFIED UNSPECIFIED UNSPECIFIED Schultze-Lutter, Frauke UNSPECIFIED UNSPECIFIED UNSPECIFIED Juckel, Georg UNSPECIFIED UNSPECIFIED UNSPECIFIED Linszen, Don UNSPECIFIED UNSPECIFIED UNSPECIFIED Dingemans, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Birchwood, Max UNSPECIFIED UNSPECIFIED UNSPECIFIED Klosterkoetter, Joachim UNSPECIFIED UNSPECIFIED UNSPECIFIED Ruhrmann, Stephan UNSPECIFIED orcid.org/0000-0002-6022-2364 UNSPECIFIED McGorry, Patrick D. UNSPECIFIED UNSPECIFIED UNSPECIFIED McGlashan, Thomas H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Knapp, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-134190
DOI:	10.1111/eip.12714
Journal or Publication Title:	Early Interv. Psychiatry
Volume:	13
Number:	4
Page Range:	S. 935 - 943
Date:	2019
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1751-7893
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SEXUAL-ABUSE; MENTAL-HEALTH; ADOLESCENTS; EXPERIENCES; BEHAVIOR; PREVALENCE; DISORDERS; SAMPLE; COMORBIDITY; SYMPTOMS Multiple languages Psychiatry Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/13419