Universität zu Köln

Liang, Hongping, Wei, Tong, Xu, Yan, Li, Linzhou, Sahu, Sunil Kumar ORCID: 0000-0002-4742-9870, Wang, Hongli, Li, Haoyuan, Fu, Xian, Zhang, Gengyun, Melkonian, Michael, Liu, Xin ORCID: 0000-0003-3256-2940, Wang, Sibo and Liu, Huan ORCID: 0000-0003-3909-0931 (2019). Phylogenomics Provides New Insights into Gains and Losses of Selenoproteins among Archaeplastida. Int. J. Mol. Sci., 20 (12). BASEL: MDPI. ISSN 1422-0067

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Abstract

Selenoproteins that contain selenocysteine (Sec) are found in all kingdoms of life. Although they constitute a small proportion of the proteome, selenoproteins play essential roles in many organisms. In photosynthetic eukaryotes, selenoproteins have been found in algae but are missing in land plants (embryophytes). In this study, we explored the evolutionary dynamics of Sec incorporation by conveying a genomic search for the Sec machinery and selenoproteins across Archaeplastida. We identified a complete Sec machinery and variable sizes of selenoproteomes in the main algal lineages. However, the entire Sec machinery was missing in the Bangiophyceae-Florideophyceae clade (BV) of Rhodoplantae (red algae) and only partial machinery was found in three species of Archaeplastida, indicating parallel loss of Sec incorporation in different groups of algae. Further analysis of genome and transcriptome data suggests that all major lineages of streptophyte algae display a complete Sec machinery, although the number of selenoproteins is low in this group, especially in subaerial taxa. We conclude that selenoproteins tend to be lost in Archaeplastida upon adaptation to a subaerial or acidic environment. The high number of redox-active selenoproteins found in some bloom-forming marine microalgae may be related to defense against viral infections. Some of the selenoproteins in these organisms may have been gained by horizontal gene transfer from bacteria.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Liang, Hongping UNSPECIFIED UNSPECIFIED UNSPECIFIED Wei, Tong UNSPECIFIED UNSPECIFIED UNSPECIFIED Xu, Yan UNSPECIFIED UNSPECIFIED UNSPECIFIED Li, Linzhou UNSPECIFIED UNSPECIFIED UNSPECIFIED Sahu, Sunil Kumar UNSPECIFIED orcid.org/0000-0002-4742-9870 UNSPECIFIED Wang, Hongli UNSPECIFIED UNSPECIFIED UNSPECIFIED Li, Haoyuan UNSPECIFIED UNSPECIFIED UNSPECIFIED Fu, Xian UNSPECIFIED UNSPECIFIED UNSPECIFIED Zhang, Gengyun UNSPECIFIED UNSPECIFIED UNSPECIFIED Melkonian, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Liu, Xin UNSPECIFIED orcid.org/0000-0003-3256-2940 UNSPECIFIED Wang, Sibo UNSPECIFIED UNSPECIFIED UNSPECIFIED Liu, Huan UNSPECIFIED orcid.org/0000-0003-3909-0931 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-138250
DOI:	10.3390/ijms20123020
Journal or Publication Title:	Int. J. Mol. Sci.
Volume:	20
Number:	12
Date:	2019
Publisher:	MDPI
Place of Publication:	BASEL
ISSN:	1422-0067
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SELENOCYSTEINE INCORPORATION; SELENIUM ACCUMULATION; SEQUENCE; ALGA; SELENOPROFILES; IDENTIFICATION; BIOCHEMISTRY; ANNOTATION; MAFFT; RNA Multiple languages Biochemistry & Molecular Biology; Chemistry, Multidisciplinary Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/13825