Universität zu Köln

Scheel, Jennifer, Schieber, Katharina, Reber, Sandra, Jank, Sabine, Eckardt, Kai-Uwe, Grundmann, Franziska, Vitinius, Frank, de Zwaan, Martina ORCID: 0000-0002-7918-6957, Bertram, Anna and Erim, Yesim (2019). Psychological processing of a kidney transplantation, perceived quality of life, and immunosuppressant medication adherence. Patient Prefer. Adherence, 13. S. 775 - 783. ALBANY: DOVE MEDICAL PRESS LTD. ISSN 1177-889X

Full text not available from this repository.

Abstract

Introduction: Though psychosocial well-being and quality of life generally improve after transplantation, a relevant proportion of patients suffers from psychosocial problems. Further analysis of the psychological coping after kidney transplantation is needed to identify patients at risk. The aim of this study was to examine the psychological response after kidney transplantation and its associations with health-related quality of life and immunosuppressant medication adherence. Materials and methods: The coping process after kidney transplantation was investigated with the Transplant Effects Questionnaire (TxEQ; subscales: worry, guilt, disclosure, adherence, responsibility) in 267 adult kidney transplant recipients >= 12 months post-transplantation. Furthermore, perceived health-related quality of life, self-reported immunosuppressant medication adherence, and sub-therapeutic immunosuppressant trough levels as biological markers of adherence were assessed. Results: Patients showed moderate scores concerning the subscales worry, guilt, and responsibility as well as high scores concerning disclosure. Except for adherence, all TxEQ subscales were associated with mental, but not with physical health-related quality of life and self-reported adherence. Sub-therapeutic immunosuppressant trough levels were significantly associated only with the TxEQ subscale worry. Conclusions: The present results suggest a conditional structure in which mental health-related quality of life is negatively associated with worries, guilt, and responsibility and positively with disclosure. Adherence seems to be a complex behavior, which is not necessarily directly associated with the psychological processing of organ transplantations. As mental health-related quality of life is related to this psychological processing, the TxEQ could be used as a screening tool for problematic psychological processing after kidney transplantation.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Scheel, Jennifer UNSPECIFIED UNSPECIFIED UNSPECIFIED Schieber, Katharina UNSPECIFIED UNSPECIFIED UNSPECIFIED Reber, Sandra UNSPECIFIED UNSPECIFIED UNSPECIFIED Jank, Sabine UNSPECIFIED UNSPECIFIED UNSPECIFIED Eckardt, Kai-Uwe UNSPECIFIED UNSPECIFIED UNSPECIFIED Grundmann, Franziska UNSPECIFIED UNSPECIFIED UNSPECIFIED Vitinius, Frank UNSPECIFIED UNSPECIFIED UNSPECIFIED de Zwaan, Martina UNSPECIFIED orcid.org/0000-0002-7918-6957 UNSPECIFIED Bertram, Anna UNSPECIFIED UNSPECIFIED UNSPECIFIED Erim, Yesim UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-139014
DOI:	10.2147/PPA.S194254
Journal or Publication Title:	Patient Prefer. Adherence
Volume:	13
Page Range:	S. 775 - 783
Date:	2019
Publisher:	DOVE MEDICAL PRESS LTD
Place of Publication:	ALBANY
ISSN:	1177-889X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ORGAN-TRANSPLANTATION; QUESTIONNAIRE TXEQ; HEALTH SURVEY; NONADHERENCE; LIVER; HEART; LUNG; VALIDATION Multiple languages Medicine, General & Internal Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/13901