Faedda, Gianni L., Baldessarini, Ross J., Marangoni, Ciro, Bechdolf, Andreas, Berk, Michael ORCID: 0000-0002-5554-6946, Birmaher, Boris, Conus, Philippe, DelBello, Melissa P., Duffy, Anne C., Hillegers, Manon H. J., Pfennig, Andrea, Post, Robert M., Preisig, Martin ORCID: 0000-0001-5689-4259, Ratheesh, Aswin, Salvatore, Paola, Tohen, Mauricio, Vazquez, Gustavo H., Vieta, Eduard ORCID: 0000-0002-0548-0053, Yatham, Lakshmi N., Youngstrom, Eric A., Van Meter, Anna and Correll, Christoph U. . An International Society of Bipolar Disorders task force report: Precursors and prodromes of bipolar disorder. Bipolar Disord.. HOBOKEN: WILEY. ISSN 1399-5618

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Abstract

Objectives To clarify the clinical features preceding the onset of bipolar disorder (BD) has become a public health priority for the prevention of high morbidity and mortality. BD remains frequently under- or misdiagnosed, and under- or mistreated, often for years. Methods We assessed the predictive value of precursors and prodromes of BD. We assessed precursors of first-lifetime manic or hypomanic episodes with/without mixed features in retrospective and prospective studies. The task force evaluated and summarized separately assessments of familial risk, premorbid personality traits, retrospective, and prospective studies. Results Cyclothymic features, a family history of BD, retrospectively reported attenuated manic symptoms, prospectively identified subthreshold symptoms of hypomania, recurrence of depression, panic anxiety and psychotic features, have been identified as clinical precursors of BD. The prodromal symptoms like [hypo]mania often appears to be long enough to encourage early identification and timely intervention. Conclusions The predictive value of any risk factor identified remains largely unknown. Prospective controlled studies are urgently needed for prevention and effective treatment.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Faedda, Gianni L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Baldessarini, Ross J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Marangoni, CiroUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bechdolf, AndreasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Berk, MichaelUNSPECIFIEDorcid.org/0000-0002-5554-6946UNSPECIFIED
Birmaher, BorisUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Conus, PhilippeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
DelBello, Melissa P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Duffy, Anne C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hillegers, Manon H. J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pfennig, AndreaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Post, Robert M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Preisig, MartinUNSPECIFIEDorcid.org/0000-0001-5689-4259UNSPECIFIED
Ratheesh, AswinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Salvatore, PaolaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tohen, MauricioUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vazquez, Gustavo H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vieta, EduardUNSPECIFIEDorcid.org/0000-0002-0548-0053UNSPECIFIED
Yatham, Lakshmi N.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Youngstrom, Eric A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Van Meter, AnnaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Correll, Christoph U.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-141181
DOI: 10.1111/bdi.12831
Journal or Publication Title: Bipolar Disord.
Publisher: WILEY
Place of Publication: HOBOKEN
ISSN: 1399-5618
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
NATIONAL EPIDEMIOLOGIC SURVEY; MAJOR DEPRESSIVE DISORDER; HELP-SEEKING ADOLESCENTS; AFFECTIVE TEMPERAMENTS; MOOD DISORDERS; RISK-FACTORS; I DISORDER; AT-RISK; PSYCHIATRIC-DISORDERS; FOLLOW-UPMultiple languages
Clinical Neurology; Neurosciences; PsychiatryMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/14118

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