Universität zu Köln

Siggel, Robert, Christofi, Eleftheria, Giasoumi, Fanouria, Adler, Werner ORCID: 0000-0001-9791-5407, Siebelmann, Sebastian, Bachmann, Bjoern, Cursiefen, Claus and Heindl, Ludwig M. (2019). Changes in Corneal Biomechanical Properties After Descemet Membrane Endothelial Keratoplasty. Cornea, 38 (8). S. 964 - 970. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1536-4798

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Abstract

Purpose: To evaluate the course of corneal biomechanical properties (corneal hysteresis and corneal resistance factor) after Descemet membrane endothelial keratoplasty (DMEK) in patients with Fuchs endothelial dystrophy (FECD). Methods: In this prospective study, we consecutively included 49 patients with FECD with an indication for DMEK. Central corneal thickness, measured using the Oculus Pentacam, and corneal hysteresis (CH) and corneal resistance factor (CRF), both measured using the Reichert Ocular Response Analyzer, were examined preoperatively, 3 months, and 6 months after DMEK. Results: CH was significantly increased 6 months postoperatively (8.66 +/- 2.50 mm Hg) compared with preoperative baseline (7.43 +/- 1.56 mm Hg). Preoperative CRF (7.89 +/- 1.68 mm Hg) increased significantly 6 months after DMEK (8.49 +/- 1.71 mm Hg). Preoperative central corneal thickness showed a significant decrease from 629 +/- 58 mm to 550 +/- 40 mm after 3 months and 535 +/- 40 mm after 6 months postoperatively. Conclusions: DMEK affects both measured corneal biomechanical properties in patients with FECD: CH and CRF. This has to be taken into account for the accuracy of intraocular pressure measurements.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Siggel, Robert UNSPECIFIED UNSPECIFIED UNSPECIFIED Christofi, Eleftheria UNSPECIFIED UNSPECIFIED UNSPECIFIED Giasoumi, Fanouria UNSPECIFIED UNSPECIFIED UNSPECIFIED Adler, Werner UNSPECIFIED orcid.org/0000-0001-9791-5407 UNSPECIFIED Siebelmann, Sebastian UNSPECIFIED UNSPECIFIED UNSPECIFIED Bachmann, Bjoern UNSPECIFIED UNSPECIFIED UNSPECIFIED Cursiefen, Claus UNSPECIFIED UNSPECIFIED UNSPECIFIED Heindl, Ludwig M. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-145672
DOI:	10.1097/ICO.0000000000001986
Journal or Publication Title:	Cornea
Volume:	38
Number:	8
Page Range:	S. 964 - 970
Date:	2019
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1536-4798
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language DYNAMIC CONTOUR TONOMETRY; OCULAR-RESPONSE-ANALYZER; INTRAOCULAR-PRESSURE; THICKNESS; GOLDMANN; HYSTERESIS; TRANSPLANTATION; KERATOCONUS; DYSTROPHY; 1ST Multiple languages Ophthalmology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/14567