Universität zu Köln

Rossoni, Alessandro W., Price, Dana C., Seger, Mark, Lyska, Dagmar, Lammers, Peter, Bhattacharya, Debashish ORCID: 0000-0003-0611-1273 and Weber, Andreas P. M. (2019). The genomes of polyextremophilic cyanidiales contain 1% horizontally transferred genes with diverse adaptive functions. eLife, 8. CAMBRIDGE: ELIFE SCIENCES PUBLICATIONS LTD. ISSN 2050-084X

Full text not available from this repository.

Abstract

The role and extent of horizontal gene transfer (HGT) in eukaryotes are hotly disputed topics that impact our understanding of the origin of metabolic processes and the role of organelles in cellular evolution. We addressed this issue by analyzing 10 novel Cyanidiales genomes and determined that 1% of their gene inventory is HGT-derived. Numerous HGT candidates share a close phylogenetic relationship with prokaryotes that live in similar habitats as the Cyanidiales and encode functions related to polyextremophily. HGT candidates differ from native genes in GC-content, number of splice sites, and gene expression. HGT candidates are more prone to loss, which may explain the absence of a eukaryotic pan-genome. Therefore, the lack of a pan-genome and cumulative effects fail to provide substantive arguments against our hypothesis of recurring HGT followed by differential loss in eukaryotes. The maintenance of 1% HGTs, even under selection for genome reduction, underlines the importance of non-endosymbiosis related foreign gene acquisition.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Rossoni, Alessandro W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Price, Dana C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Seger, Mark UNSPECIFIED UNSPECIFIED UNSPECIFIED Lyska, Dagmar UNSPECIFIED UNSPECIFIED UNSPECIFIED Lammers, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Bhattacharya, Debashish UNSPECIFIED orcid.org/0000-0003-0611-1273 UNSPECIFIED Weber, Andreas P. M. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-147655
DOI:	10.7554/eLife.45017
Journal or Publication Title:	eLife
Volume:	8
Date:	2019
Publisher:	ELIFE SCIENCES PUBLICATIONS LTD
Place of Publication:	CAMBRIDGE
ISSN:	2050-084X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ALGA CYANIDIOSCHYZON-MEROLAE; YELLOWSTONE-NATIONAL-PARK; GALDIERIA-SULPHURARIA; BETA-GALACTOSIDASE; COMPATIBLE SOLUTE; RED ALGAE; SEQUENCE; PROTEIN; CLONING; ANNOTATION Multiple languages Biology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/14765