Universität zu Köln

Maschmeyer, Georg, De Greef, Julien ORCID: 0000-0003-0200-1237, Mellinghoff, Sibylle C., Nosari, Annamaria, Thiebaut-Bertrand, Anne, Bergeron, Anne, Franquet, Tomas, Blijlevens, Nicole M. A. and Maertens, Johan A. (2019). Infections associated with immunotherapeutic and molecular targeted agents in hematology and oncology. A position paper by the European Conference on Infections in Leukemia (ECIL). Leukemia, 33 (4). S. 844 - 863. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-5551

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Abstract

A multitude of new agents for the treatment of hematologic malignancies has been introduced over the past decade. Hematologists, infectious disease specialists, stem cell transplant experts, pulmonologists and radiologists have met within the framework of the European Conference on Infections in Leukemia (ECIL) to provide a critical state-of-the-art on infectious complications associated with immunotherapeutic and molecular targeted agents used in clinical routine. For brentuximab vedotin, blinatumomab, CTLA4- and PD-1/PD-L1-inhibitors as well as for ibrutinib, idelalisib, HDAC inhibitors, mTOR inhibitors, ruxolitinib, and venetoclax, a detailed review of data available until August 2018 has been conducted, and specific recommendations for prophylaxis, diagnostic and differential diagnostic procedures as well as for clinical management have been developed.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Maschmeyer, Georg UNSPECIFIED UNSPECIFIED UNSPECIFIED De Greef, Julien UNSPECIFIED orcid.org/0000-0003-0200-1237 UNSPECIFIED Mellinghoff, Sibylle C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Nosari, Annamaria UNSPECIFIED UNSPECIFIED UNSPECIFIED Thiebaut-Bertrand, Anne UNSPECIFIED UNSPECIFIED UNSPECIFIED Bergeron, Anne UNSPECIFIED UNSPECIFIED UNSPECIFIED Franquet, Tomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Blijlevens, Nicole M. A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Maertens, Johan A. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-152361
DOI:	10.1038/s41375-019-0388-x
Journal or Publication Title:	Leukemia
Volume:	33
Number:	4
Page Range:	S. 844 - 863
Date:	2019
Publisher:	NATURE PUBLISHING GROUP
Place of Publication:	LONDON
ISSN:	1476-5551
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; CHRONIC LYMPHOCYTIC-LEUKEMIA; PNEUMOCYSTIS-JIROVECII PNEUMONIA; IMMUNE CHECKPOINT BLOCKADE; STEM-CELL TRANSPLANTATION; B-VIRUS REACTIVATION; INTERNATIONAL WORKING GROUP; FUNCTION IN-VITRO; 3-YEAR FOLLOW-UP; BRENTUXIMAB VEDOTIN Multiple languages Oncology; Hematology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/15236