Universität zu Köln

Miebach, Lisa, Wolfsgruber, Steffen, Frommann, Ingo, Fliessbach, Klaus, Jessen, Frank, Buckley, Rachel and Wagner, Michael ORCID: 0000-0003-2589-6440 (2019). Cognitive Complaints in Memory Clinic Patients and in Depressive Patients: An Interpretative Phenomenological Analysis. Gerontologist, 59 (2). S. 290 - 303. CARY: OXFORD UNIV PRESS INC. ISSN 1758-5341

Full text not available from this repository.

Abstract

Background and Objectives Cognitive complaints are discussed as early signs of Alzheimer's disease (AD). However, they are also very common in cognitively normal older adults and in patients with depression. Qualitative, interview-based approaches might be useful to identify those features of cognitive complaints specific for the experiences of cognitive decline in preclinical or prodromal AD versus those complaints typically reported by depressed patients. Research Design and Methods A semi-structured interview was administered to 21 cognitively normal older adults (HC), 18 nondemented memory clinic patients (MC), and 11 patients with a major depression (MD), all above 55 years. Interpretative phenomenological analysis (IPA) was applied to the interview transcripts to develop emerging complaint themes in each group. To identify thematic correspondence and possibly novel, hitherto unappreciated themes, the extracted complaint categories were compared with the neurocognitive domains in the DSM-5 and the content of the Everyday Cognition questionnaire (E-Cog). Results IPA yielded 18 cognitive complaint categories in MC, 10 in depressive patients, and 10 categories in the HC group. Several themes were common across groups, but some were group-specific, for example, spatial disorientation was only reported in MC patients. Some of these MC-specific themes were neither represented by DSM-5 domains nor by the E-Cog. Discussion and Implications We report a comprehensive qualitative description of cognitive complaints in old age which could help to develop questionnaires or structured interviews to better assess AD-related subjective cognitive decline. This may help to increase specificity in selecting high-risk subjects in research settings and improve clinical judgment of diverse cognitive complaints types mentioned by their patients.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Miebach, Lisa UNSPECIFIED UNSPECIFIED UNSPECIFIED Wolfsgruber, Steffen UNSPECIFIED UNSPECIFIED UNSPECIFIED Frommann, Ingo UNSPECIFIED UNSPECIFIED UNSPECIFIED Fliessbach, Klaus UNSPECIFIED UNSPECIFIED UNSPECIFIED Jessen, Frank UNSPECIFIED UNSPECIFIED UNSPECIFIED Buckley, Rachel UNSPECIFIED UNSPECIFIED UNSPECIFIED Wagner, Michael UNSPECIFIED orcid.org/0000-0003-2589-6440 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-152615
DOI:	10.1093/geront/gnx208
Journal or Publication Title:	Gerontologist
Volume:	59
Number:	2
Page Range:	S. 290 - 303
Date:	2019
Publisher:	OXFORD UNIV PRESS INC
Place of Publication:	CARY
ISSN:	1758-5341
Language:	English
Faculty:	Faculty of Management, Economy and Social Sciences
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MILD ALZHEIMERS-DISEASE; NEUROPSYCHOLOGICAL ASSESSMENT; AMYLOID DEPOSITION; OLDER-ADULTS; IMPAIRMENT; DEMENTIA; DECLINE; SYMPTOMS; ANOSOGNOSIA; AWARENESS Multiple languages Gerontology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/15261