Universität zu Köln

Zimmermann, Maximilian, Bendas, Gerd and Feldmann, Georg (2019). Leukemia caused by collision with a wild pig? Dtsch. Med. Wochenschr., 144 (5). S. 335 - 340. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1439-4413

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Abstract

History A 23 years old, previously healthy woman was admitted to our clinic with neutropenic fever to rule out acute leukemia. Upon admission the patient reported that a few days ago the carcass of a pig had fallen on her from above, so that she experienced strong back pain. Findings and Diagnosis The blood count showed thrombocytopenia and marked neutropenia of 0.04G/L. Moreover, laboratory work up demonstrated increased C-reactive protein, procalcitonin as well as serum creatinine levels. Therapy and course Broad antiinfective therapy was initiated immediately. During the further course of disease the patient developed signs of acute cholecystitis, which was managed conservatively. Only after repeated specific investigation and after initially denying, the patient reported to have taken 1 g of metamizole as self-medication after her initial accident. All symptoms and laboratory parameters gradually improved and finally completely resolved to normal, and the patient could be released from hospital after seven days. Conclusions In retrospect all signs and symptoms reported here can be interpreted as an infectious complication during an episode of agranulocytosis caused by a single dose of metamizole, underscoring the importance of carefully judging indication when using this otherwise highly useful substance.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Zimmermann, Maximilian UNSPECIFIED UNSPECIFIED UNSPECIFIED Bendas, Gerd UNSPECIFIED UNSPECIFIED UNSPECIFIED Feldmann, Georg UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-155412
Journal or Publication Title:	Dtsch. Med. Wochenschr.
Volume:	144
Number:	5
Page Range:	S. 335 - 340
Date:	2019
Publisher:	GEORG THIEME VERLAG KG
Place of Publication:	STUTTGART
ISSN:	1439-4413
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language DRUG-INDUCED AGRANULOCYTOSIS Multiple languages Medicine, General & Internal Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/15541