Universität zu Köln

Katsara, Maria-Alexandra and Nothnagel, Michael ORCID: 0000-0001-8305-7114 (2019). True colors: A literature review on the spatial distribution of eye and hair pigmentation. Forensic Sci. Int.-Genet., 39. S. 109 - 119. CLARE: ELSEVIER IRELAND LTD. ISSN 1878-0326

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Abstract

DNA-based prediction of externally visible characteristics has become an established approach in forensic genetics, with the aim of tracing individuals who are potentially unknown to the investigating authorities but without using this prediction as evidence in court. While a number of prediction models have been proposed, use of prior probabilities in those models has largely been absent. Here, we aim at compiling information on the spatial distribution of eye and hair coloration in order to use this as prior knowledge to improve prediction accuracy. To this end, we conducted a detailed literature review and created maps showing the eye and hair pigmentation prevalence both by countries with available information and by interpolation in order to obtain prior estimates for populations without available data. Furthermore, we assessed the association between these two traits in a very large data set. A strong limitation was the quite low amount of available data, especially outside Europe. We hope that our results will facilitate the improvement of already existing and of novel prediction methods for pigmentation traits and induce further studies on the spatial distribution of these traits.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Katsara, Maria-Alexandra UNSPECIFIED UNSPECIFIED UNSPECIFIED Nothnagel, Michael UNSPECIFIED orcid.org/0000-0001-8305-7114 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-156114
DOI:	10.1016/j.fsigen.2019.01.001
Journal or Publication Title:	Forensic Sci. Int.-Genet.
Volume:	39
Page Range:	S. 109 - 119
Date:	2019
Publisher:	ELSEVIER IRELAND LTD
Place of Publication:	CLARE
ISSN:	1878-0326
Language:	English
Faculty:	Faculty of Mathematics and Natural Sciences
Divisions:	Faculty of Mathematics and Natural Sciences > Department of Biology > Institute for Genetics
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language GENOME-WIDE ASSOCIATION; DNA-BASED EYE; SKIN PIGMENTATION; HIRISPLEX SYSTEM; SIMULTANEOUS PREDICTION; GENETIC-DETERMINANTS; OCA2; EVOLUTION; MELANOMA; HERC2 Multiple languages Genetics & Heredity; Medicine, Legal Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/15611