Universität zu Köln

Buehl, Linda, Abel, Thomas, Wolf, Florian, Oberste, Max, Bloch, Wilhelm, Hallek, Michael, Elter, Thomas and Zimmer, Philipp (2019). Feasibility and Potential Benefits of an Exercise Intervention in a Male With Down Syndrome Undergoing High-Dose Chemotherapy for Acute Lymphoblastic Leukemia: A Case Report. Integr. Cancer Ther., 18. THOUSAND OAKS: SAGE PUBLICATIONS INC. ISSN 1552-695X

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Abstract

In patients with hematological malignancies, exercise is studied as a supportive measure with potential benefits on therapy and disease-related side effects. However, clinical trials have not yet integrated people with Down syndrome (DS), although this disability is associated with an increased risk for hematological malignancies. Therefore, we examined safety and feasibility of a mixed-modality exercise intervention in a male with DS undergoing high-dose chemotherapy for acute lymphoblastic leukemia. Furthermore, physical capacity and fatigue were assessed. Exercise sessions took place 3 times/wk over a 5-week period. Adherence to the exercise program was 100%, and no serious adverse events occurred. In contrast to the training sessions, applied endurance testing was not feasible. Furthermore, maintenance of fatigue level was observed. In conclusion, cancer patients with DS suffering from leukemia should not be excluded from physical activity or exercise programs.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Buehl, Linda UNSPECIFIED UNSPECIFIED UNSPECIFIED Abel, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Wolf, Florian UNSPECIFIED UNSPECIFIED UNSPECIFIED Oberste, Max UNSPECIFIED UNSPECIFIED UNSPECIFIED Bloch, Wilhelm UNSPECIFIED UNSPECIFIED UNSPECIFIED Hallek, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Elter, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Zimmer, Philipp UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-156356
DOI:	10.1177/1534735419832358
Journal or Publication Title:	Integr. Cancer Ther.
Volume:	18
Date:	2019
Publisher:	SAGE PUBLICATIONS INC
Place of Publication:	THOUSAND OAKS
ISSN:	1552-695X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language HEART-RATE; CANCER; INDIVIDUALS; CAPACITY; MEDICINE; CHILDREN Multiple languages Oncology; Integrative & Complementary Medicine Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/15635