Universität zu Köln

Lohmann, Philipp ORCID: 0000-0002-5360-046X, Werner, Jan-Michael, Shah, N. Jon ORCID: 0000-0002-8151-6169, Fink, Gereon R. ORCID: 0000-0002-8230-1856, Langen, Karl-Josef ORCID: 0000-0003-1101-5075 and Galldiks, Norbert ORCID: 0000-0002-2485-1796 (2019). Combined Amino Acid Positron Emission Tomography and Advanced Magnetic Resonance Imaging in Glioma Patients. Cancers, 11 (2). BASEL: MDPI. ISSN 2072-6694

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Abstract

Imaging techniques such as positron emission tomography (PET) and magnetic resonance imaging (MRI) provide valuable information about brain tumor patients. Particularly amino acid PET, advanced MRI techniques, and combinations thereof are of great interest for the non-invasive assessment of biological characteristics in patients with primary or secondary brain cancer. A methodological innovation that potentially advances research in patients with brain tumors is the increasing availability of hybrid PET/MRI systems, which enables the simultaneous acquisition of both imaging modalities. Furthermore, the advent of ultra-high field MRI scanners operating at magnetic field strengths of 7 T or more will allow further development of metabolic MR imaging at higher resolution. This review focuses on the combination of amino acid PET with MR spectroscopic imaging, perfusion- and diffusion-weighted imaging, as well as chemical exchange saturation transfer in patients with high-grade gliomas, especially glioblastomas.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Lohmann, Philipp UNSPECIFIED orcid.org/0000-0002-5360-046X UNSPECIFIED Werner, Jan-Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Shah, N. Jon UNSPECIFIED orcid.org/0000-0002-8151-6169 UNSPECIFIED Fink, Gereon R. UNSPECIFIED orcid.org/0000-0002-8230-1856 UNSPECIFIED Langen, Karl-Josef UNSPECIFIED orcid.org/0000-0003-1101-5075 UNSPECIFIED Galldiks, Norbert UNSPECIFIED orcid.org/0000-0002-2485-1796 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-157291
DOI:	10.3390/cancers11020153
Journal or Publication Title:	Cancers
Volume:	11
Number:	2
Date:	2019
Publisher:	MDPI
Place of Publication:	BASEL
ISSN:	2072-6694
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language DIFFUSION-WEIGHTED MRI; HIGH-GRADE GLIOMAS; BRAIN-TUMOR; IN-VIVO; C-11-METHIONINE PET; SPATIAL CORRELATION; RADIATION NECROSIS; CEREBRAL GLIOMAS; CONVENTIONAL MRI; F-18-FET PET Multiple languages Oncology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/15729